Comparative

Human gene

LYST lysosomal trafficking regulator

ENSG00000143669 on Ensembl

1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.

Animal diseases

By each group's best natural-model score, highest first. How the score works.

OMIA group Name Species Animal gene Ortholog The chain reached Best score
185 Chediak-Higashi syndrome domestic cat LYST one to one Target evidence 74.9
for Chediak-Higashi syndrome
185 Chediak-Higashi syndrome domestic cattle LYST one to one Target evidence 74.9
for Chediak-Higashi syndrome

Target evidence

Each Open Targets association between this gene and a human disease that a disease group reached.

Human disease Mondo Score Evidence
Chediak-Higashi syndrome MONDO:0008963 0.85 3,773

Drugs

Each ChEMBL drug that acts on this gene.

No ChEMBL drug acts on this gene, among the genes with target evidence.