Human gene
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 2097 | Ataxia, spinocerebellar, ITPR1-related | dog | ITPR1 | one to one | Target evidence |
57.9
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| aniridia-cerebellar ataxia-intellectual disability syndrome | MONDO:0008795 | 0.83 | 156 |
| spinocerebellar ataxia type 29 | MONDO:0007298 | 0.81 | 131 |
| spinocerebellar ataxia type 15/16 | MONDO:0011694 | 0.77 | 140 |
Drugs
Each ChEMBL drug that acts on this gene.
No ChEMBL drug acts on this gene, among the genes with target evidence.