Comparative

Human gene

GRM1 glutamate receptor, metabotropic 1

ENSG00000152822 on Ensembl

1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.

Animal diseases

By each group's best natural-model score, highest first. How the score works.

OMIA group Name Species Animal gene Ortholog The chain reached Best score
78 Ataxia, cerebellar, neonatal, GRM1-related dog GRM1 one to one Target evidence 60.9
for autosomal recessive spinocerebellar ataxia 13

Target evidence

Each Open Targets association between this gene and a human disease that a disease group reached.

Human disease Mondo Score Evidence
autosomal recessive spinocerebellar ataxia 13 MONDO:0013905 0.77 63
spinocerebellar ataxia 44 MONDO:0033479 0.68 50

Drugs

Each ChEMBL drug that acts on this gene.

No ChEMBL drug acts on this gene, among the genes with target evidence.