Comparative

Human gene

ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif 3

ENSG00000156140 on Ensembl

2 disease groups in OMIA reach this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.

Animal diseases

By each group's best natural-model score, highest first. How the score works.

OMIA group Name Species Animal gene Ortholog The chain reached Best score
1562 Pulmonary hypoplasia with anasarca, ADAMTS3-related domestic cattle ADAMTS3 one to one Human gene 32.0
for hennekam lymphangiectasia-lymphedema syndrome 3
1562 Pulmonary hypoplasia with anasarca, ADAMTS3-related sheep ADAMTS3 one to one Human gene 32.0
for hennekam lymphangiectasia-lymphedema syndrome 3
1893 Upper airway syndrome dog ADAMTS3 one to one Animal disease only

Target evidence

Each Open Targets association between this gene and a human disease that a disease group reached.

Open Targets links this gene to none of the human diseases the disease groups reached.

Drugs

Each ChEMBL drug that acts on this gene.

No ChEMBL drug acts on this gene, among the genes with target evidence.