Human gene
RPGR retinitis pigmentosa GTPase regulator
2 disease groups in OMIA reach this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 831 | Retinal atrophy, progressive, X-linked, type 1 | dog | RPGR | one to one | Target evidence |
53.9
|
| 1518 | Retinal atrophy, progressive, X-linked, type 2 | dog | RPGR | one to one | Target evidence |
53.9
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| retinitis pigmentosa 3 | MONDO:0010227 | 0.71 | 287 |
| X-linked cone-rod dystrophy 1 | MONDO:0010566 | 0.67 | 69 |
Drugs
Each ChEMBL drug that acts on this gene.
No ChEMBL drug acts on this gene, among the genes with target evidence.