Human gene
ACAN aggrecan
2 disease groups in OMIA reach this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 1271 | Dwarfism, ACAN-related | domestic cattle | ACAN | one to one | Target evidence |
61.3
|
| 702 | Nanomelia | chicken | ACAN | one to one | Target evidence |
55.3
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| spondyloepimetaphyseal dysplasia, aggrecan type | MONDO:0013014 | 0.75 | 99 |
| spondyloepiphyseal dysplasia, Kimberley type | MONDO:0012019 | 0.74 | 95 |
Drugs
Each ChEMBL drug that acts on this gene.
No ChEMBL drug acts on this gene, among the genes with target evidence.