Human gene
XDH xanthine dehydrogenase
1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 2445 | Xanthinuria, type I | dog | XDH | one to one | Drug |
60.2
|
| 2445 | Xanthinuria, type I | domestic cat | XDH | one to one | Drug |
60.2
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| xanthinuria type I | MONDO:0010209 | 0.73 | 499 |
Drugs
Each ChEMBL drug that acts on this gene.
| Drug | How | Latest stage |
|---|---|---|
| Allopurinol | inhibitor | Approved |
| Bendazac | inhibitor | Approved |
| Febuxostat | inhibitor | Approved |
| Topiroxostat | inhibitor | Approved |
| Oxypurinol | inhibitor | Phase 2/3 |
The drug data is ChEMBL's, under CC BY-SA 3.0, and came through Open Targets release 26.09.