Human gene
MPZ myelin protein zero
1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 2739 | Polyneuropathy, hypomyelinating, MPZ-related | dog | MPZ | one to one | Target evidence |
58.2
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| Charcot-Marie-Tooth disease type 1B | MONDO:0007307 | 0.83 | 280 |
| Charcot-Marie-Tooth disease type 3 | MONDO:0007790 | 0.83 | 166 |
| Charcot-Marie-Tooth disease type 2I | MONDO:0011889 | 0.81 | 54 |
| Charcot-Marie-Tooth disease type 2J | MONDO:0011903 | 0.76 | 34 |
| Charcot-Marie-Tooth disease dominant intermediate D | MONDO:0011909 | 0.72 | 76 |
Drugs
Each ChEMBL drug that acts on this gene.
No ChEMBL drug acts on this gene, among the genes with target evidence.