Human gene
SV2A synaptic vesicle glycoprotein 2A
1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 344 | Epilepsy | chicken | SV2A | one to one | Drug |
67.5
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| idiopathic generalized epilepsy | MONDO:0005579 | 0.36 | 11 |
| Unverricht-Lundborg syndrome | MONDO:0009698 | 0.32 | 3 |
| juvenile myoclonic epilepsy | MONDO:0009696 | 0.01 | 2 |
Drugs
Each ChEMBL drug that acts on this gene.
| Drug | How | Latest stage |
|---|---|---|
| Brivaracetam | modulator | Approved |
| Levetiracetam | modulator | Approved |
| Padsevonil | modulator | Phase 3 |
| Seletracetam | modulator | Phase 3 |
The drug data is ChEMBL's, under CC BY-SA 3.0, and came through Open Targets release 26.09.