Human gene
NLRP3 NLR family, pyrin domain containing 3
1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 2464 | Cryopyrin-associated periodic syndrome, NLRP3-related | pig | NLRP3 | one to one | Target evidence |
59.4
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| CINCA syndrome | MONDO:0011776 | 0.84 | 572 |
| Muckle-Wells syndrome | MONDO:0008633 | 0.80 | 510 |
| familial cold autoinflammatory syndrome 1 | MONDO:0007349 | 0.80 | 290 |
Drugs
Each ChEMBL drug that acts on this gene.
No ChEMBL drug acts on this gene, among the genes with target evidence.