Comparative

Human gene

ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1

ENSG00000165029 on Ensembl

1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.

Animal diseases

By each group's best natural-model score, highest first. How the score works.

OMIA group Name Species Animal gene Ortholog The chain reached Best score
42 Analphalipoproteinaemia, ABCA1-related chicken ABCA1 one to one Drug 65.9
for Tangier disease
42 Analphalipoproteinaemia, ABCA1-related golden hamster Abca1 one to one Drug 65.9
for Tangier disease

Target evidence

Each Open Targets association between this gene and a human disease that a disease group reached.

Human disease Mondo Score Evidence
Tangier disease MONDO:0008783 0.84 722

Drugs

Each ChEMBL drug that acts on this gene.

Drug How Latest stage
Probucol inhibitor Approved

The drug data is ChEMBL's, under CC BY-SA 3.0, and came through Open Targets release 26.09.