Human gene
OTX2 orthodenticle homeobox 2
1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 2227 | Otocephaly, OTX2-related | sheep | OTX2 | one to many | Target evidence |
49.6
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| syndromic microphthalmia type 5 | MONDO:0012413 | 0.82 | 77 |
| pituitary hormone deficiency, combined, 6 | MONDO:0013518 | 0.65 | 43 |
Drugs
Each ChEMBL drug that acts on this gene.
No ChEMBL drug acts on this gene, among the genes with target evidence.