Human gene
FBN1 fibrillin 1
1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 628 | Marfan syndrome, FBN1-related | dog | FBN1 | one to one | Target evidence |
88.0
|
| 628 | Marfan syndrome, FBN1-related | domestic cattle | FBN1 | one to one | Target evidence |
88.0
|
| 628 | Marfan syndrome, FBN1-related | pig | FBN1 | one to one | Target evidence |
88.0
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| Marfan syndrome | MONDO:0007947 | 0.89 | 11,321 |
| MASS syndrome | MONDO:0011431 | 0.74 | 341 |
Drugs
Each ChEMBL drug that acts on this gene.
No ChEMBL drug acts on this gene, among the genes with target evidence.