Comparative

Human gene

MECP2 methyl-CpG binding protein 2

ENSG00000169057 on Ensembl

1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.

Animal diseases

By each group's best natural-model score, highest first. How the score works.

OMIA group Name Species Animal gene Ortholog The chain reached Best score
2406 Rett syndrome, MECP2-related crab-eating macaque MECP2 one to one Target evidence 84.9
for Rett syndrome
2406 Rett syndrome, MECP2-related Rhesus monkey MECP2 one to one Target evidence 84.9
for Rett syndrome
2406 Rett syndrome, MECP2-related white-tufted-ear marmoset MECP2 one to one Target evidence 84.9
for Rett syndrome

Target evidence

Each Open Targets association between this gene and a human disease that a disease group reached.

Human disease Mondo Score Evidence
Rett syndrome MONDO:0010726 0.88 4,583

Drugs

Each ChEMBL drug that acts on this gene.

No ChEMBL drug acts on this gene, among the genes with target evidence.