Human gene
AR androgen receptor
1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 991 | Androgen insensitivity syndrome (AIS) | chicken | AR | one to one | Drug |
51.9
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| androgen insensitivity syndrome | MONDO:0019154 | 0.84 | 1,730 |
Drugs
Each ChEMBL drug that acts on this gene.
| Drug | How | Latest stage |
|---|---|---|
| Abiraterone | antagonist | Approved |
| Apalutamide | antagonist | Approved |
| Bicalutamide | antagonist | Approved |
| Clascoterone | antagonist | Approved |
| Cyproterone Acetate | antagonist | Approved |
| Danazol | agonist | Approved |
| Darolutamide | antagonist | Approved |
| Enzalutamide | antagonist | Approved |
| Ethylestrenol | agonist | Approved |
| Fluoxymesterone | agonist | Approved |
| Flutamide | antagonist | Approved |
| Methandrostenolone | agonist | Approved |
| Methyltestosterone | agonist | Approved |
| Nilutamide | antagonist | Approved |
| Oxandrolone | agonist | Approved |
| Oxymetholone | agonist | Approved |
| Stanozolol | agonist | Approved |
| Testosterone | agonist | Approved |
| Testosterone Cypionate | agonist | Approved |
| Testosterone Enanthate | agonist | Approved |
| Testosterone Propionate | agonist | Approved |
| Testosterone Undecanoate | agonist | Approved |
| Enobosarm | modulator | Phase 3 |
| Galeterone | antagonist | Phase 3 |
| Nandrolone Decanoate | agonist | Phase 3 |
| Pruxelutamide | antagonist | Phase 3 |
| Rezvilutamide | antagonist | Phase 3 |
| Cr 1447 | agonist | Phase 2 |
| Dimethylcurcumin | degrader | Phase 2 |
| Gsk2881078 | modulator | Phase 2 |
| He3235 | modulator | Phase 2 |
| Ly2452473 | modulator | Phase 2 |
| Mk-0773 | modulator | Phase 2 |
| Seviteronel | antagonist | Phase 2 |
| Vk5211 | modulator | Phase 2 |
| Apc-100 | antagonist | Phase 1/2 |
| Azd3514 | modulator | Phase 1 |
| Glpg0492 | modulator | Phase 1 |
| Gsk2849466 | modulator | Phase 1 |
| Lgd-2941 | modulator | Phase 1 |
| Dromostanolone Propionate | agonist | Unknown |
| Nandrolone Phenpropionate | agonist | Unknown |
The drug data is ChEMBL's, under CC BY-SA 3.0, and came through Open Targets release 26.09.