Human gene
GLB1 galactosidase, beta 1
1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 402 | Gangliosidosis, GM1 | dog | GLB1 | one to one | Target evidence |
64.7
|
| 402 | Gangliosidosis, GM1 | domestic cat | GLB1 | one to one | Target evidence |
64.7
|
| 402 | Gangliosidosis, GM1 | sheep | GLB1 | one to one | Target evidence |
64.7
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| mucopolysaccharidosis type 4B | MONDO:0009660 | 0.85 | 1,329 |
| GM1 gangliosidosis type 1 | MONDO:0009260 | 0.85 | 306 |
| GM1 gangliosidosis type 3 | MONDO:0009262 | 0.84 | 197 |
| GM1 gangliosidosis type 2 | MONDO:0009261 | 0.84 | 208 |
Drugs
Each ChEMBL drug that acts on this gene.
No ChEMBL drug acts on this gene, among the genes with target evidence.