Comparative

Human gene

RAG2 recombination activating gene 2

ENSG00000175097 on Ensembl

1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.

Animal diseases

By each group's best natural-model score, highest first. How the score works.

OMIA group Name Species Animal gene Ortholog The chain reached Best score
1574 Severe combined immunodeficiency disease, autosomal, T cell-negative, B cell-negative, NK cell-positive pig RAG2 one to one Target evidence 62.0
for severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, NK cell-positive

Target evidence

Each Open Targets association between this gene and a human disease that a disease group reached.

Human disease Mondo Score Evidence
severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, NK cell-positive MONDO:0011086 0.79 597

Drugs

Each ChEMBL drug that acts on this gene.

No ChEMBL drug acts on this gene, among the genes with target evidence.