Human gene
PLEC plectin
1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 2080 | Epidermolysis bullosa, simplex, PLEC-related | dog | PLEC | one to one | Target evidence |
56.7
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| epidermolysis bullosa simplex 5B, with muscular dystrophy | MONDO:0009181 | 0.79 | 5,865 |
| epidermolysis bullosa simplex 5A, Ogna type | MONDO:0007555 | 0.77 | 5,844 |
| epidermolysis bullosa simplex 5C, with pyloric atresia | MONDO:0012807 | 0.75 | 5,850 |
| epidermolysis bullosa simplex with nail dystrophy | MONDO:0014661 | 0.69 | 5,852 |
Drugs
Each ChEMBL drug that acts on this gene.
No ChEMBL drug acts on this gene, among the genes with target evidence.