Human gene
PLA2G6 phospholipase A2 group VI
1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 2105 | Neuroaxonal dystrophy, PLA2G6-related | dog | PLA2G6 | one to one | Target evidence |
79.5
|
| 2105 | Neuroaxonal dystrophy, PLA2G6-related | sheep | PLA2G6 | one to one | Target evidence |
79.5
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| neurodegeneration with brain iron accumulation 2A | MONDO:0024457 | 0.86 | 1,185 |
| autosomal recessive Parkinson disease 14 | MONDO:0013060 | 0.82 | 151 |
| neurodegeneration with brain iron accumulation 2B | MONDO:0012444 | 0.73 | 192 |
Drugs
Each ChEMBL drug that acts on this gene.
No ChEMBL drug acts on this gene, among the genes with target evidence.