Comparative

Human gene

SRY sex determining region Y

ENSG00000184895 on Ensembl

1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.

Animal diseases

By each group's best natural-model score, highest first. How the score works.

OMIA group Name Species Animal gene Ortholog The chain reached Best score
1230 XY sex reversal, SRY-related domestic cattle SRY one to one Target evidence 68.8
for 46,XY sex reversal 1
1230 XY sex reversal, SRY-related pig SRY one to many Target evidence 68.8
for 46,XY sex reversal 1

Target evidence

Each Open Targets association between this gene and a human disease that a disease group reached.

Human disease Mondo Score Evidence
46,XY sex reversal 1 MONDO:0020712 0.82 85

Drugs

Each ChEMBL drug that acts on this gene.

No ChEMBL drug acts on this gene, among the genes with target evidence.