Comparative

Human gene

PRKN parkin RBR E3 ubiquitin protein ligase

ENSG00000185345 on Ensembl

1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.

Animal diseases

By each group's best natural-model score, highest first. How the score works.

OMIA group Name Species Animal gene Ortholog The chain reached Best score
2748 Parkinson disease, PRKN-related pig PRKN one to one Human gene 5.0
for autosomal recessive juvenile Parkinson disease 2
2748 Parkinson disease, PRKN-related Rhesus monkey PRKN one to one Human gene 5.0
for autosomal recessive juvenile Parkinson disease 2

Target evidence

Each Open Targets association between this gene and a human disease that a disease group reached.

Open Targets links this gene to none of the human diseases the disease groups reached.

Drugs

Each ChEMBL drug that acts on this gene.

No ChEMBL drug acts on this gene, among the genes with target evidence.