Human gene

KRT5 keratin 5

1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.

Animal diseases

By each group's best natural-model score, highest first. How the score works.

OMIA group	Name	Species	Animal gene	Ortholog	The chain reached	Best score
2081	Epidermolysis bullosa simplex, KRT5-related	domestic cattle	KRT5	one to one	Target evidence	61.9 for epidermolysis bullosa simplex 2C, localized
2081	Epidermolysis bullosa simplex, KRT5-related	Rhesus monkey	KRT5	one to one	Target evidence	61.9 for epidermolysis bullosa simplex 2C, localized

Target evidence

Each Open Targets association between this gene and a human disease that a disease group reached.

Human disease	Mondo	Score	Evidence
epidermolysis bullosa simplex 2C, localized	MONDO:0030527	0.77	55
epidermolysis bullosa simplex 2A, generalized severe	MONDO:0030489	0.76	37
epidermolysis bullosa simplex 2B, generalized intermediate	MONDO:0030525	0.76	38
epidermolysis bullosa simplex 2F, with mottled pigmentation	MONDO:0007556	0.73	21
Dowling-Degos disease 1	MONDO:0024534	0.70	47
epidermolysis bullosa simplex 2d, generalized, intermediate or severe, autosomal recessive	MONDO:0030535	0.69	19
epidermolysis bullosa simplex 2E, with migratory circinate erythema	MONDO:0012258	0.65	16

Drugs

Each ChEMBL drug that acts on this gene.

No ChEMBL drug acts on this gene, among the genes with target evidence.