Comparative

Human gene

KRT10 keratin 10, type I

ENSG00000186395 on Ensembl

1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.

Animal diseases

By each group's best natural-model score, highest first. How the score works.

OMIA group Name Species Animal gene Ortholog The chain reached Best score
1415 Hyperkeratosis, epidermolytic dog KRT10 one to one Target evidence 57.5
for congenital reticular ichthyosiform erythroderma

Target evidence

Each Open Targets association between this gene and a human disease that a disease group reached.

Human disease Mondo Score Evidence
congenital reticular ichthyosiform erythroderma MONDO:0012208 0.73 48
ichthyosis, annular epidermolytic 1 MONDO:0100303 0.65 16

Drugs

Each ChEMBL drug that acts on this gene.

No ChEMBL drug acts on this gene, among the genes with target evidence.