Comparative

Human gene

CLCN1 chloride channel, voltage-sensitive 1

ENSG00000188037 on Ensembl

1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.

Animal diseases

By each group's best natural-model score, highest first. How the score works.

OMIA group Name Species Animal gene Ortholog The chain reached Best score
698 Myotonia dog CLCN1 one to one Target evidence 81.1
for Thomsen and Becker disease
698 Myotonia goat CLCN1 one to one Target evidence 81.1
for Thomsen and Becker disease
698 Myotonia horse CLCN1 one to one Target evidence 81.1
for Thomsen and Becker disease
698 Myotonia pig CLCN1 one to one Target evidence 81.1
for Thomsen and Becker disease
698 Myotonia sheep CLCN1 one to one Target evidence 81.1
for Thomsen and Becker disease

Target evidence

Each Open Targets association between this gene and a human disease that a disease group reached.

Human disease Mondo Score Evidence
myotonia congenita, autosomal recessive MONDO:0009715 0.76 68
Thomsen and Becker disease MONDO:0009710 0.74 1,961

Drugs

Each ChEMBL drug that acts on this gene.

No ChEMBL drug acts on this gene, among the genes with target evidence.