Human gene
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
2 disease groups in OMIA reach this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 1450 | Congenital muscular dystonia 1 | domestic cattle | ATP2A1 | one to one | Drug |
63.4
|
| 1464 | Pseudomyotonia, congenital | domestic cattle | ATP2A1 | one to one | Drug |
63.4
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| Brody myopathy | MONDO:0010977 | 0.77 | 845 |
Drugs
Each ChEMBL drug that acts on this gene.
| Drug | How | Latest stage |
|---|---|---|
| Mipsagargin | inhibitor | Phase 2 |
The drug data is ChEMBL's, under CC BY-SA 3.0, and came through Open Targets release 26.09.