Comparative

Human gene

NF1 neurofibromin 1

ENSG00000196712 on Ensembl

2 disease groups in OMIA reach this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.

Animal diseases

By each group's best natural-model score, highest first. How the score works.

OMIA group Name Species Animal gene Ortholog The chain reached Best score
716 Neurofibromatosis, generic domestic cattle NF1 one to one Target evidence 90.9
for neurofibromatosis type 1
2241 Neurofibromatosis, type 1 pig NF1 one to one Target evidence 89.9
for neurofibromatosis type 1

Target evidence

Each Open Targets association between this gene and a human disease that a disease group reached.

Human disease Mondo Score Evidence
neurofibromatosis type 1 MONDO:0018975 0.88 15,452

Drugs

Each ChEMBL drug that acts on this gene.

No ChEMBL drug acts on this gene, among the genes with target evidence.