Human gene
LAMB3 laminin, beta 3
1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 2269 | Epidermolysis bullosa, junctionalis, LAMB3-related | dog | LAMB3 | one to one | Drug |
62.4
|
| 2269 | Epidermolysis bullosa, junctionalis, LAMB3-related | sheep | LAMB3 | one to one | Drug |
62.4
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| junctional epidermolysis bullosa, non-Herlitz type | MONDO:0009180 | 0.80 | 135 |
| junctional epidermolysis bullosa Herlitz type | MONDO:0009182 | 0.78 | 262 |
Drugs
Each ChEMBL drug that acts on this gene.
| Drug | How | Latest stage |
|---|---|---|
| Ocriplasmin | hydrolytic enzyme | Approved |
The drug data is ChEMBL's, under CC BY-SA 3.0, and came through Open Targets release 26.09.