Human gene
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 2179 | Stargardt disease 1 | dog | ABCA4 | one to one | Target evidence |
78.2
|
| 2179 | Stargardt disease 1 | pig | ABCA4 | one to one | Target evidence |
78.2
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| Stargardt disease | MONDO:0019353 | 0.84 | 976 |
| severe early-childhood-onset retinal dystrophy | MONDO:0009549 | 0.83 | 1,211 |
Drugs
Each ChEMBL drug that acts on this gene.
No ChEMBL drug acts on this gene, among the genes with target evidence.