Human gene
HEXA hexosaminidase A (alpha polypeptide)
1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 1461 | Gangliosidosis, GM2, type I (B variant) | dog | HEXA | one to one | Target evidence |
85.2
|
| 1461 | Gangliosidosis, GM2, type I (B variant) | domestic cattle | HEXA | one to one | Target evidence |
85.2
|
| 1461 | Gangliosidosis, GM2, type I (B variant) | pig | HEXA | one to one | Target evidence |
85.2
|
| 1461 | Gangliosidosis, GM2, type I (B variant) | sheep | HEXA | one to one | Target evidence |
85.2
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| Tay-Sachs disease | MONDO:0010100 | 0.86 | 1,540 |
Drugs
Each ChEMBL drug that acts on this gene.
No ChEMBL drug acts on this gene, among the genes with target evidence.