Human gene
INS insulin
1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 279 | Diabetes mellitus | pig | INS | one to one | Target evidence |
65.7
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| type 1 diabetes mellitus | MONDO:0005147 | 0.73 | 29,547 |
| type 2 diabetes mellitus | MONDO:0005148 | 0.59 | 59,656 |
| maternally-inherited diabetes and deafness | MONDO:0010785 | 0.02 | 55 |
| maturity-onset diabetes of the young type 2 | MONDO:0007453 | 0.01 | 17 |
Drugs
Each ChEMBL drug that acts on this gene.
No ChEMBL drug acts on this gene, among the genes with target evidence.