OMIA group 1216
Coat colour, roan
The chain
From the animal disease to the drugs. The page shows what each step found and where the chain stopped. It does not say whether the animal is a model of a human disease.
-
Animal disease
Reached
OMIA records it in 1 species entry marked as a defect.
-
Human disease
Stopped here
Neither OMIA's own Mondo link nor its OMIM numbers lead to a Mondo disease.
-
Human gene
Not reached
The chain stopped before this step.
-
Target evidence
Not reached
The chain stopped before this step.
-
Drugs
Not reached
The chain stopped before this step.
The chain stopped at Human disease: Neither OMIA's own Mondo link nor its OMIM numbers lead to a Mondo disease.
Natural-model score
How complete and how well supported the chain to each human disease is, out of 100, by stated rules. It does not say that the animal is a validated model of the human disease. How the score works.
This group reaches no human disease, so it has no score.
Species
The chain follows only the species entries that OMIA marks as a defect.
| Species | Scientific name | OMIA entry | A defect |
|---|---|---|---|
| alpaca | Vicugna pacos | OMIA:001216-30538 | No, not counted |
| dog | Canis lupus familiaris | OMIA:001216-9615 | No, not counted |
| domestic cattle | Bos taurus | OMIA:001216-9913 | No, not counted |
| goat | Capra hircus | OMIA:001216-9925 | Unknown, not counted |
| horse | Equus caballus | OMIA:001216-9796 | No, not counted |
| pig | Sus scrofa | OMIA:001216-9823 | No, not counted |
| sheep | Ovis aries | OMIA:001216-9940 | Yes |
Genes
Each gene OMIA records for a species entry, and the human gene it reaches through Ensembl's orthologs.
| Species | Animal gene | Human gene | Ortholog |
|---|---|---|---|
| sheep | No gene | OMIA records no gene for this species entry. | |
| alpaca Not a defect, not counted | KITLG KIT ligand NCBI Gene 102546113 | Ensembl does not know this NCBI Gene identifier. | |
| dog Not a defect, not counted | USH2A Usher syndrome 2A (autosomal recessive, mild) NCBI Gene 488593 | USH2A Ensembl | one to one |
| domestic cattle Not a defect, not counted | KITLG KIT ligand NCBI Gene 281885 | KITLG Ensembl | one to one |
| goat Not a defect, not counted | No gene | OMIA records no gene for this species entry. | |
| horse Not a defect, not counted | KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog NCBI Gene 100009704 | KIT Ensembl | one to one |
| pig Not a defect, not counted | KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog NCBI Gene 396810 | KIT Ensembl | one to one |
Human diseases
Two routes lead from an OMIA group to a Mondo human disease: OMIA's own Mondo link, and the group's OMIM numbers through Mondo's cross-references.
- OMIA's own Mondo link: OMIA links the group to no Mondo disease.
- OMIA's OMIM numbers: No current Mondo disease is the same disease as the group's OMIM numbers.
The chain did not reach a human disease.
Target evidence
Each Open Targets association between one of the group's human genes and one of its human diseases, with its overall score and the score for each kind of evidence.
The chain did not reach target evidence.
Drugs
The chain did not reach the drugs.