Human disease
hemophilia B
Mondo defines it as: “Hemophilia B is a form of hemophilia characterized by spontaneous or prolonged hemorrhages due to factor IX deficiency.”
1 disease group in OMIA reaches this disease, through OMIA's own Mondo link or its OMIM numbers. The page shows the chain. It does not say whether an animal is a model of this disease.
Animal diseases
By natural-model score for this disease, highest first. The score says how complete and how well supported each chain is, by stated rules. How the score works.
| OMIA group | Name | Found by | Species | The chain reached | Score |
|---|---|---|---|---|---|
| 438 | Haemophilia B | Both routes | 4 | Drug |
96.0
|
Human genes
Each human gene of these disease groups that Open Targets links to this disease.
| Human gene | Score | Evidence |
|---|---|---|
| F9 | 0.89 | 2,020 |
Drugs tested for this disease
Each ChEMBL drug that has been tested for this disease, and the human genes above it acts on, if any. Open Targets gives some drugs, such as most enzyme replacement therapies, no target gene.
| Drug | Acts on | Latest stage for this disease |
|---|---|---|
| Albutrepenonacog Alfa | F9 | Approved |
| Coagulation Factor Ix Human | F9 | Approved |
| Coagulation Factor Ix Recombinant Human | F9 | Approved |
| Concizumab | None of these genes | Approved |
| Eftrenonacog Alfa | F9 | Approved |
| Eptacog Alfa (Activated) | None of these genes | Approved |
| Eptacog Beta (Activated) | None of these genes | Approved |
| Etranacogene Dezaparvovec | F9 | Approved |
| Fidanacogene Elaparvovec | F9 | Approved |
| Marstacimab | None of these genes | Approved |
| Nonacog Beta Pegol | F9 | Approved |
| Antihemophilic Factor, Pegylated (Mw 20000) Human Sequence Recombinant | None of these genes | Phase 3 |
| Bemiltenase Alfa | None of these genes | Phase 3 |
| Efmoroctocog Alfa | None of these genes | Phase 3 |
| Fitusiran | None of these genes | Phase 3 |
| Lonoctocog Alfa | None of these genes | Phase 3 |
| Marzeptacog Alfa (Activated) | None of these genes | Phase 3 |
| Moroctocog Alfa | None of these genes | Phase 3 |
| Octocog Alfa | None of these genes | Phase 3 |
| Ataluren | None of these genes | Phase 2 |
| Bay-1093884 | None of these genes | Phase 2 |
| Verbrinacogene Setparvovec | None of these genes | Phase 1/2 |
| Arc-19499 | None of these genes | Phase 1 |
The drug data is ChEMBL's, under CC BY-SA 3.0, and came through Open Targets release 26.09.