Comparative

Human gene

TNNT2 troponin T type 2 (cardiac)

ENSG00000118194 on Ensembl

1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.

Animal diseases

By each group's best natural-model score, highest first. How the score works.

OMIA group Name Species Animal gene Ortholog The chain reached Best score
162 Cardiomyopathy, dilated turkey TNNT2 one to one Drug 53.6
for Barth syndrome

Target evidence

Each Open Targets association between this gene and a human disease that a disease group reached.

Human disease Mondo Score Evidence
dilated cardiomyopathy 1A MONDO:0007269 0.07 4
arrhythmogenic right ventricular dysplasia 1 MONDO:0007152 0.07 3
dilated cardiomyopathy 2A MONDO:0012746 0.05 1
dilated cardiomyopathy 3B MONDO:0010542 0.04 1
Barth syndrome MONDO:0010543 0.03 3

Drugs

Each ChEMBL drug that acts on this gene.

Drug How Latest stage
Levosimendan positive modulator Approved

The drug data is ChEMBL's, under CC BY-SA 3.0, and came through Open Targets release 26.09.