Human gene
PRNP prion protein
1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 944 | Spongiform encephalopathy, susceptibility/resistance to | domestic cattle | PRNP | one to one | Target evidence |
48.7
|
| 944 | Spongiform encephalopathy, susceptibility/resistance to | goat | PRNP | one to one | Target evidence |
48.7
|
| 944 | Spongiform encephalopathy, susceptibility/resistance to | sheep | PRNP | one to one | Target evidence |
48.7
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| kuru | MONDO:0006825 | 0.39 | 51 |
Drugs
Each ChEMBL drug that acts on this gene.
No ChEMBL drug acts on this gene, among the genes with target evidence.