Human disease
lung cancer
Mondo defines it as: “A malignant neoplasm involving the lung.”
1 disease group in OMIA reaches this disease, through OMIA's own Mondo link or its OMIM numbers. The page shows the chain. It does not say whether an animal is a model of this disease.
Animal diseases
By natural-model score for this disease, highest first. The score says how complete and how well supported each chain is, by stated rules. How the score works.
| OMIA group | Name | Found by | Species | The chain reached | Score |
|---|---|---|---|---|---|
| 1990 | Cancer, TP53-related | OMIA's OMIM numbers | 5 | Drug |
79.6
|
Human genes
Each human gene of these disease groups that Open Targets links to this disease.
| Human gene | Score | Evidence |
|---|---|---|
| KRAS | 0.65 | 4,284 |
| TP53 | 0.40 | 5,142 |
Drugs tested for this disease
Each ChEMBL drug that has been tested for this disease, and the human genes above it acts on, if any. Open Targets gives some drugs, such as most enzyme replacement therapies, no target gene.
| Drug | Acts on | Latest stage for this disease |
|---|---|---|
| Alectinib | None of these genes | Approved |
| Atezolizumab | None of these genes | Approved |
| Cemiplimab | None of these genes | Approved |
| Etoposide | None of these genes | Approved |
| Methotrexate | None of these genes | Approved |
| Olmutinib | None of these genes | Approved |
| Prinomastat | None of these genes | Approved |
| Trametinib | None of these genes | Approved |
| Abemaciclib | None of these genes | Phase 3 |
| Berahyaluronidase Alfa | None of these genes | Phase 3 |
| Bevacizumab | None of these genes | Phase 3 |
| Capmatinib | None of these genes | Phase 3 |
| Carboplatin | None of these genes | Phase 3 |
| Cisplatin | None of these genes | Phase 3 |
| Custirsen | None of these genes | Phase 3 |
| Dalteparin Sodium | None of these genes | Phase 3 |
| Dimesna | None of these genes | Phase 3 |
| Docetaxel Anhydrous | None of these genes | Phase 3 |
| Durvalumab | None of these genes | Phase 3 |
| Erlotinib | None of these genes | Phase 3 |
| Gemcitabine | None of these genes | Phase 3 |
| Ipilimumab | None of these genes | Phase 3 |
| Karenitecin | None of these genes | Phase 3 |
| Lurbinectedin | None of these genes | Phase 3 |
| Marimastat | None of these genes | Phase 3 |
| Necitumumab | None of these genes | Phase 3 |
| Nivolumab | None of these genes | Phase 3 |
| Osimertinib | None of these genes | Phase 3 |
| Paclitaxel | None of these genes | Phase 3 |
| Pembrolizumab | None of these genes | Phase 3 |
| Pemetrexed | None of these genes | Phase 3 |
| Rociletinib | None of these genes | Phase 3 |
| Sintilimab | None of these genes | Phase 3 |
| Sotorasib | KRAS | Phase 3 |
| Tanomastat | None of these genes | Phase 3 |
| Tarlatamab | None of these genes | Phase 3 |
| Topotecan | None of these genes | Phase 3 |
| Uridine Triphosphate | None of these genes | Phase 3 |
| Vibostolimab | None of these genes | Phase 3 |
| Vinorelbine | None of these genes | Phase 3 |
| Zoledronic Acid Anhydrous | None of these genes | Phase 3 |
| Aumolertinib | None of these genes | Phase 2/3 |
| Doxorubicin | None of these genes | Phase 2/3 |
| Endostatin | None of these genes | Phase 2/3 |
| Levobupivacaine | None of these genes | Phase 2/3 |
| (+/-)Nicotine | None of these genes | Phase 2/3 |
| Nicotine | None of these genes | Phase 2/3 |
| Varenicline | None of these genes | Phase 2/3 |
| 4-Demethyl-4-Cholesteryloxycarbonylpenclomedine | None of these genes | Phase 2 |
| Adagrasib | KRAS | Phase 2 |
| Adebrelimab | None of these genes | Phase 2 |
| Afatinib | None of these genes | Phase 2 |
| Agatolimod | None of these genes | Phase 2 |
| Aldesleukin | None of these genes | Phase 2 |
| Antineoplaston A10 | None of these genes | Phase 2 |
| Apatorsen | None of these genes | Phase 2 |
| Apatorsen Sodium | None of these genes | Phase 2 |
| Ascorbic Acid | None of these genes | Phase 2 |
| Aspirin | None of these genes | Phase 2 |
| Axelopran | None of these genes | Phase 2 |
| Azacitidine | None of these genes | Phase 2 |
| Bortezomib | None of these genes | Phase 2 |
| Brivanib Alaninate | None of these genes | Phase 2 |
| Bromelains | None of these genes | Phase 2 |
| Cabazitaxel | None of these genes | Phase 2 |
| Cabozantinib | None of these genes | Phase 2 |
| Camrelizumab | None of these genes | Phase 2 |
| Catequentinib | None of these genes | Phase 2 |
| Certolizumab | None of these genes | Phase 2 |
| Cyclophosphamide Anhydrous | None of these genes | Phase 2 |
| Dabrafenib | None of these genes | Phase 2 |
| Dalpiciclib | None of these genes | Phase 2 |
| Dexamethasone | None of these genes | Phase 2 |
| Diclofenac | None of these genes | Phase 2 |
| Doconexent | None of these genes | Phase 2 |
| Ecadotril | None of these genes | Phase 2 |
| Elraglusib | None of these genes | Phase 2 |
| Enalapril | None of these genes | Phase 2 |
| Entinostat | None of these genes | Phase 2 |
| Entrectinib | None of these genes | Phase 2 |
| Everolimus | None of these genes | Phase 2 |
| Filgrastim | None of these genes | Phase 2 |
| Firmonertinib | None of these genes | Phase 2 |
| Fludarabine | None of these genes | Phase 2 |
| Fluorouracil | None of these genes | Phase 2 |
| Fulvestrant | None of these genes | Phase 2 |
| Gefitinib | None of these genes | Phase 2 |
| Gimistotug | None of these genes | Phase 2 |
| Grapiprant | None of these genes | Phase 2 |
| Hydrocortisone | None of these genes | Phase 2 |
| Icosapent | None of these genes | Phase 2 |
| Icotinib | None of these genes | Phase 2 |
| Idarubicin | None of these genes | Phase 2 |
| Ifosfamide | None of these genes | Phase 2 |
| Imatinib | None of these genes | Phase 2 |
| Infliximab | None of these genes | Phase 2 |
| Interferon Alfa-2b | None of these genes | Phase 2 |
| Irinotecan | None of these genes | Phase 2 |
| Lapatinib | None of these genes | Phase 2 |
| Lazertinib | None of these genes | Phase 2 |
| Lenvatinib | None of these genes | Phase 2 |
| Letrozole | None of these genes | Phase 2 |
| Lomustine | None of these genes | Phase 2 |
| Lucitanib | None of these genes | Phase 2 |
| Metformin | None of these genes | Phase 2 |
| Methylprednisolone | None of these genes | Phase 2 |
| Nelfinavir | None of these genes | Phase 2 |
| Nitrogen | None of these genes | Phase 2 |
| Olaparib | None of these genes | Phase 2 |
| Oxazolidine | None of these genes | Phase 2 |
| Palbociclib | None of these genes | Phase 2 |
| Patritumab Deruxtecan | None of these genes | Phase 2 |
| Paxalisib | None of these genes | Phase 2 |
| Pazopanib | None of these genes | Phase 2 |
| Pegenzileukin | None of these genes | Phase 2 |
| Pemigatinib | None of these genes | Phase 2 |
| Phenylacetic Acid | None of these genes | Phase 2 |
| Platinum | None of these genes | Phase 2 |
| Plicamycin | None of these genes | Phase 2 |
| Ponatinib | None of these genes | Phase 2 |
| Prednisolone | None of these genes | Phase 2 |
| Prednisone | None of these genes | Phase 2 |
| Pyrotinib | None of these genes | Phase 2 |
| Ramucirumab | None of these genes | Phase 2 |
| Ranpirnase | None of these genes | Phase 2 |
| Relatlimab | None of these genes | Phase 2 |
| Retaspimycin | None of these genes | Phase 2 |
| Sacubitril | None of these genes | Phase 2 |
| Salirasib | KRAS | Phase 2 |
| Sargramostim | None of these genes | Phase 2 |
| Selumetinib | None of these genes | Phase 2 |
| Serplulimab | None of these genes | Phase 2 |
| Sorafenib | None of these genes | Phase 2 |
| Tariquidar | None of these genes | Phase 2 |
| Tegtociclib | None of these genes | Phase 2 |
| Temozolomide | None of these genes | Phase 2 |
| Tipiracil | None of these genes | Phase 2 |
| Tislelizumab | None of these genes | Phase 2 |
| Toripalimab | None of these genes | Phase 2 |
| Trastuzumab | None of these genes | Phase 2 |
| Tremelimumab | None of these genes | Phase 2 |
| Tyrosine | None of these genes | Phase 2 |
| Valsartan | None of these genes | Phase 2 |
| Vemurafenib | None of these genes | Phase 2 |
| Zanidatamab | None of these genes | Phase 2 |
| 2x-121 | None of these genes | Phase 1/2 |
| Auranofin | None of these genes | Phase 1/2 |
| Batoprotafib | None of these genes | Phase 1/2 |
| Binimetinib | None of these genes | Phase 1/2 |
| Bintrafusp Alfa | None of these genes | Phase 1/2 |
| Biw-8962 | None of these genes | Phase 1/2 |
| Bms-986156 | None of these genes | Phase 1/2 |
| Bt-5528 | None of these genes | Phase 1/2 |
| Camptothecin | None of these genes | Phase 1/2 |
| Crizotinib | None of these genes | Phase 1/2 |
| Davamotecan Pegadexamer | None of these genes | Phase 1/2 |
| Decitabine | None of these genes | Phase 1/2 |
| Gebasaxturev | None of these genes | Phase 1/2 |
| Idronoxil | None of these genes | Phase 1/2 |
| Immunocytokine Nhs-Il12 | None of these genes | Phase 1/2 |
| L-Dos47 | None of these genes | Phase 1/2 |
| Lorlatinib | None of these genes | Phase 1/2 |
| Neo-201 | None of these genes | Phase 1/2 |
| Nintedanib | None of these genes | Phase 1/2 |
| Ny-Eso-1 | None of these genes | Phase 1/2 |
| Pegargiminase | None of these genes | Phase 1/2 |
| Pemlimogene Merolisbac | None of these genes | Phase 1/2 |
| Pexipepimut-S | None of these genes | Phase 1/2 |
| Porfimer Sodium | None of these genes | Phase 1/2 |
| Rg-4733 | None of these genes | Phase 1/2 |
| Rivoceranib | None of these genes | Phase 1/2 |
| Sirolimus | None of these genes | Phase 1/2 |
| Tifcemalimab | None of these genes | Phase 1/2 |
| Valemetostat | None of these genes | Phase 1/2 |
| Verteporfin | None of these genes | Phase 1/2 |
| Vociprotafib | None of these genes | Phase 1/2 |
| Aflibercept | None of these genes | Phase 1 |
| Alisertib | None of these genes | Phase 1 |
| Alvocidib | None of these genes | Phase 1 |
| Anastrozole | None of these genes | Phase 1 |
| Avutometinib | None of these genes | Phase 1 |
| Bifidobacterium Spp. | None of these genes | Phase 1 |
| Brigimadlin | None of these genes | Phase 1 |
| Budesonide | None of these genes | Phase 1 |
| Cabiralizumab | None of these genes | Phase 1 |
| Calcitriol | None of these genes | Phase 1 |
| Carotuximab | None of these genes | Phase 1 |
| Cediranib | None of these genes | Phase 1 |
| Celecoxib | None of these genes | Phase 1 |
| Ceritinib | None of these genes | Phase 1 |
| Cetuximab | None of these genes | Phase 1 |
| Charcoal, Activated | None of these genes | Phase 1 |
| Cholecalciferol | None of these genes | Phase 1 |
| Darleukin | None of these genes | Phase 1 |
| Diazepinomicin | None of these genes | Phase 1 |
| Dotmp Sm-153 | None of these genes | Phase 1 |
| Enfortumab Vedotin | None of these genes | Phase 1 |
| Exarafenib | None of these genes | Phase 1 |
| Ezabenlimab | None of these genes | Phase 1 |
| Ferric Carboxymaltose | None of these genes | Phase 1 |
| Ferric Oxyhydroxide | None of these genes | Phase 1 |
| Ferrous Sulfate | None of these genes | Phase 1 |
| Fianlimab | None of these genes | Phase 1 |
| Formoterol | None of these genes | Phase 1 |
| Galunisertib | None of these genes | Phase 1 |
| Hydralazine | None of these genes | Phase 1 |
| Ibi-939 | None of these genes | Phase 1 |
| Iron Isomaltoside 1000 | None of these genes | Phase 1 |
| Istiratumab | None of these genes | Phase 1 |
| Lanerkitug | None of these genes | Phase 1 |
| Lapachone | None of these genes | Phase 1 |
| Linsitinib | None of these genes | Phase 1 |
| Lurtotecan | None of these genes | Phase 1 |
| Magnesium | None of these genes | Phase 1 |
| Mogamulizumab | None of these genes | Phase 1 |
| Nanrilkefusp Alfa | None of these genes | Phase 1 |
| Nerofe | None of these genes | Phase 1 |
| Niraparib | None of these genes | Phase 1 |
| Onvatilimab | None of these genes | Phase 1 |
| Padeliporfin | None of these genes | Phase 1 |
| Pemvidutide | None of these genes | Phase 1 |
| Refametinib | None of these genes | Phase 1 |
| Regorafenib | None of these genes | Phase 1 |
| Romidepsin | None of these genes | Phase 1 |
| Sacituzumab Tirumotecan | None of these genes | Phase 1 |
| Samotolisib | None of these genes | Phase 1 |
| Sapanisertib | None of these genes | Phase 1 |
| Sasanlimab | None of these genes | Phase 1 |
| Sephb4-Hsa | None of these genes | Phase 1 |
| Seribantumab | None of these genes | Phase 1 |
| Sotigalimab | None of these genes | Phase 1 |
| Sunitinib | None of these genes | Phase 1 |
| Talazoparib | None of these genes | Phase 1 |
| Tegafur | None of these genes | Phase 1 |
| Tenatumomab | None of these genes | Phase 1 |
| Thiosulfuric Acid | None of these genes | Phase 1 |
| Tucotuzumab Celmoleukin | None of these genes | Phase 1 |
| Valproic Acid | None of these genes | Phase 1 |
| Veliparib | None of these genes | Phase 1 |
| Vorinostat | None of these genes | Phase 1 |
| Xentuzumab | None of these genes | Phase 1 |
| Bupropion | None of these genes | Early phase 1 |
| Dacomitinib Anhydrous | None of these genes | Early phase 1 |
| Ethiodized Oil | None of these genes | Early phase 1 |
| Desflurane | None of these genes | Unknown |
| Dexmedetomidine | None of these genes | Unknown |
| Leuprolide | None of these genes | Unknown |
| Mirtazapine | None of these genes | Unknown |
| Nedaplatin | None of these genes | Unknown |
| Nimotuzumab | None of these genes | Unknown |
| Penpulimab | None of these genes | Unknown |
| Propofol | None of these genes | Unknown |
| Sevoflurane | None of these genes | Unknown |
The drug data is ChEMBL's, under CC BY-SA 3.0, and came through Open Targets release 26.09.