Human disease
acute myeloid leukemia
Mondo defines it as: “Acute myeloid leukemia (AML) is a group of neoplasms arising from precursor cells committed to the myeloid cell-line differentiation. All of them are characterized by clonal expansion of myeloid blasts. AML manifests by fever, pallor, anemia, hemorrhages and recurrent infections.”
1 disease group in OMIA reaches this disease, through OMIA's own Mondo link or its OMIM numbers. The page shows the chain. It does not say whether an animal is a model of this disease.
Animal diseases
By natural-model score for this disease, highest first. The score says how complete and how well supported each chain is, by stated rules. How the score works.
| OMIA group | Name | Found by | Species | The chain reached | Score |
|---|---|---|---|---|---|
| 1990 | Cancer, TP53-related | OMIA's OMIM numbers | 5 | Drug |
83.3
|
Human genes
Each human gene of these disease groups that Open Targets links to this disease.
| Human gene | Score | Evidence |
|---|---|---|
| KRAS | 0.75 | 618 |
| TP53 | 0.72 | 3,572 |
Drugs tested for this disease
Each ChEMBL drug that has been tested for this disease, and the human genes above it acts on, if any. Open Targets gives some drugs, such as most enzyme replacement therapies, no target gene.
| Drug | Acts on | Latest stage for this disease |
|---|---|---|
| Azacitidine | None of these genes | Approved |
| Cytarabine | None of these genes | Approved |
| Daunorubicin | None of these genes | Approved |
| Enasidenib | None of these genes | Approved |
| Gemtuzumab Ozogamicin | None of these genes | Approved |
| Gilteritinib | None of these genes | Approved |
| Glasdegib | None of these genes | Approved |
| Histamine | None of these genes | Approved |
| Idarubicin | None of these genes | Approved |
| Ivosidenib | None of these genes | Approved |
| Melphalan | None of these genes | Approved |
| Midostaurin | None of these genes | Approved |
| Olutasidenib | None of these genes | Approved |
| Quizartinib | None of these genes | Approved |
| Sargramostim | None of these genes | Approved |
| Tagraxofusp | None of these genes | Approved |
| 2-Mercaptoethanesulfonic Acid | None of these genes | Phase 3 |
| Aclarubicin | None of these genes | Phase 3 |
| Aldesleukin | None of these genes | Phase 3 |
| Alemtuzumab | None of these genes | Phase 3 |
| Amonafide | None of these genes | Phase 3 |
| Amsacrine | None of these genes | Phase 3 |
| Antilymphocyte Immunoglobulin (Horse) | None of these genes | Phase 3 |
| Apg-2575 | None of these genes | Phase 3 |
| Arsenic Trioxide | None of these genes | Phase 3 |
| Asparaginase | None of these genes | Phase 3 |
| Asparaginase Erwinia Chrysanthemi | None of these genes | Phase 3 |
| Bleximenib | None of these genes | Phase 3 |
| Bortezomib | None of these genes | Phase 3 |
| Busulfan | None of these genes | Phase 3 |
| Carmustine | None of these genes | Phase 3 |
| Caspofungin | None of these genes | Phase 3 |
| Cedazuridine | None of these genes | Phase 3 |
| Cladribine | None of these genes | Phase 3 |
| Clofarabine | None of these genes | Phase 3 |
| Cpi 613 | None of these genes | Phase 3 |
| Crenolanib | None of these genes | Phase 3 |
| Cyclophosphamide Anhydrous | None of these genes | Phase 3 |
| Cyclosporine | None of these genes | Phase 3 |
| Dasatinib Anhydrous | None of these genes | Phase 3 |
| Decitabine | None of these genes | Phase 3 |
| Dexamethasone | None of these genes | Phase 3 |
| Dexrazoxane | None of these genes | Phase 3 |
| Dociparstat Sodium | None of these genes | Phase 3 |
| Elacytarabine | None of these genes | Phase 3 |
| Entospletinib | None of these genes | Phase 3 |
| Epoetin Alfa | None of these genes | Phase 3 |
| Etoposide | None of these genes | Phase 3 |
| Filgrastim | None of these genes | Phase 3 |
| Fludarabine | None of these genes | Phase 3 |
| Fludarabine Phosphate | None of these genes | Phase 3 |
| Galinpepimut-S | None of these genes | Phase 3 |
| Guadecitabine | None of these genes | Phase 3 |
| Hydrocortisone | None of these genes | Phase 3 |
| Hydroxyurea | None of these genes | Phase 3 |
| Idasanutlin | TP53 | Phase 3 |
| Interferon | None of these genes | Phase 3 |
| Interferon Alfa | None of these genes | Phase 3 |
| Interferon Alfa-2b | None of these genes | Phase 3 |
| Iodine I 131 Apamistamab | None of these genes | Phase 3 |
| Laromustine | None of these genes | Phase 3 |
| Lenalidomide | None of these genes | Phase 3 |
| Lenograstim | None of these genes | Phase 3 |
| Lintuzumab | None of these genes | Phase 3 |
| Lomustine | None of these genes | Phase 3 |
| Magrolimab | None of these genes | Phase 3 |
| Methotrexate | None of these genes | Phase 3 |
| Methylprednisolone | None of these genes | Phase 3 |
| Methylprednisolone Hemisuccinate | None of these genes | Phase 3 |
| Mitoxantrone | None of these genes | Phase 3 |
| Mocravimod | None of these genes | Phase 3 |
| Molgramostim | None of these genes | Phase 3 |
| Mycophenolate Mofetil | None of these genes | Phase 3 |
| Norethandrolone | None of these genes | Phase 3 |
| Oblimersen Sodium | None of these genes | Phase 3 |
| Omacetaxine Mepesuccinate | None of these genes | Phase 3 |
| Omidubicel | None of these genes | Phase 3 |
| Panobinostat | None of these genes | Phase 3 |
| Pegfilgrastim | None of these genes | Phase 3 |
| Peginterferon Alfa-2a | None of these genes | Phase 3 |
| Pevonedistat | None of these genes | Phase 3 |
| Pr1 Leukemia Peptide Vaccine | None of these genes | Phase 3 |
| Pracinostat | None of these genes | Phase 3 |
| Ranosidenib | None of these genes | Phase 3 |
| Recombinant Human Thrombopoietin | None of these genes | Phase 3 |
| Regramostim | None of these genes | Phase 3 |
| Revumenib | None of these genes | Phase 3 |
| Rigosertib | None of these genes | Phase 3 |
| Rituximab | None of these genes | Phase 3 |
| Ruserontinib | None of these genes | Phase 3 |
| Sapacitabine | None of these genes | Phase 3 |
| Selinexor | None of these genes | Phase 3 |
| Sirolimus | None of these genes | Phase 3 |
| Sorafenib | None of these genes | Phase 3 |
| Tacrolimus Anhydrous | None of these genes | Phase 3 |
| Thioguanine | None of these genes | Phase 3 |
| Thiotepa | None of these genes | Phase 3 |
| Tipifarnib | None of these genes | Phase 3 |
| Tretinoin | None of these genes | Phase 3 |
| Tucidinostat | None of these genes | Phase 3 |
| Uproleselan | None of these genes | Phase 3 |
| Vadastuximab Talirine | None of these genes | Phase 3 |
| Valspodar | None of these genes | Phase 3 |
| Venetoclax | None of these genes | Phase 3 |
| Visilizumab | None of these genes | Phase 3 |
| Vorinostat | None of these genes | Phase 3 |
| Vosaroxin | None of these genes | Phase 3 |
| Ziftomenib | None of these genes | Phase 3 |
| Zosuquidar | None of these genes | Phase 3 |
| Barasertib | None of these genes | Phase 2/3 |
| Ibrutinib | None of these genes | Phase 2/3 |
| Mycophenolic Acid | None of these genes | Phase 2/3 |
| Naxtarubicin | None of these genes | Phase 2/3 |
| Nivolumab | None of these genes | Phase 2/3 |
| Pivekimab Sunirine | None of these genes | Phase 2/3 |
| Rivogenlecleucel | None of these genes | Phase 2/3 |
| Semustine | None of these genes | Phase 2/3 |
| Talacotuzumab | None of these genes | Phase 2/3 |
| Abatacept | None of these genes | Phase 2 |
| Acetylcysteine | None of these genes | Phase 2 |
| Adavosertib | None of these genes | Phase 2 |
| Aeg-35156 | None of these genes | Phase 2 |
| Aflibercept | None of these genes | Phase 2 |
| Alisertib | None of these genes | Phase 2 |
| Alovudine | None of these genes | Phase 2 |
| Alvocidib | None of these genes | Phase 2 |
| Amifostine | None of these genes | Phase 2 |
| Aminopterin | None of these genes | Phase 2 |
| Ammonium Trichlorotellurate | None of these genes | Phase 2 |
| Amphotericin B | None of these genes | Phase 2 |
| Antroquinonol | None of these genes | Phase 2 |
| Ascorbic Acid | None of these genes | Phase 2 |
| Aslan-003 | None of these genes | Phase 2 |
| Aspacytarabine | None of these genes | Phase 2 |
| Avapritinib | None of these genes | Phase 2 |
| Axitinib | None of these genes | Phase 2 |
| Belinostat | None of these genes | Phase 2 |
| Bemcentinib | None of these genes | Phase 2 |
| Bendamustine | None of these genes | Phase 2 |
| Bevacizumab | None of these genes | Phase 2 |
| Bexarotene | None of these genes | Phase 2 |
| Bisantrene | None of these genes | Phase 2 |
| Blinatumomab | None of these genes | Phase 2 |
| Briquilimab | None of these genes | Phase 2 |
| Bryostatin 1 | None of these genes | Phase 2 |
| Calaspargase Pegol | None of these genes | Phase 2 |
| Camidanlumab Tesirine | None of these genes | Phase 2 |
| Camrelizumab | None of these genes | Phase 2 |
| Carboplatin | None of these genes | Phase 2 |
| Cediranib | None of these genes | Phase 2 |
| Cenersen | TP53 | Phase 2 |
| Cenersen Sodium | TP53 | Phase 2 |
| Cholecalciferol | None of these genes | Phase 2 |
| Choline Magnesium Trisalicylate | None of these genes | Phase 2 |
| Cilengitide | None of these genes | Phase 2 |
| Cobicistat | None of these genes | Phase 2 |
| Crisantaspase | None of these genes | Phase 2 |
| Crizotinib | None of these genes | Phase 2 |
| Cusatuzumab | None of these genes | Phase 2 |
| Daratumumab | None of these genes | Phase 2 |
| Deferasirox | None of these genes | Phase 2 |
| Denileukin Diftitox | None of these genes | Phase 2 |
| Desoxyribonuclease | None of these genes | Phase 2 |
| Dinaciclib | None of these genes | Phase 2 |
| Docetaxel Anhydrous | None of these genes | Phase 2 |
| Dornase Alfa | None of these genes | Phase 2 |
| Doxorubicin | None of these genes | Phase 2 |
| Durvalumab | None of these genes | Phase 2 |
| E-7820 | None of these genes | Phase 2 |
| Edetate Calcium Disodium Anhydrous | None of these genes | Phase 2 |
| Edicotinib | None of these genes | Phase 2 |
| Eltrombopag | None of these genes | Phase 2 |
| Entinostat | None of these genes | Phase 2 |
| Eprenetapopt | TP53 | Phase 2 |
| Erlotinib | None of these genes | Phase 2 |
| Erythromycin | None of these genes | Phase 2 |
| Everolimus | None of these genes | Phase 2 |
| Ficlatuzumab | None of these genes | Phase 2 |
| Fish Oil Triglycerides | None of these genes | Phase 2 |
| Flotetuzumab | None of these genes | Phase 2 |
| Gataparsen | None of these genes | Phase 2 |
| Gedatolisib | None of these genes | Phase 2 |
| Gefitinib | None of these genes | Phase 2 |
| Gemcitabine | None of these genes | Phase 2 |
| Gemtuzumab | None of these genes | Phase 2 |
| Glycerol Phenylbutyrate | None of these genes | Phase 2 |
| Gti-2040 | None of these genes | Phase 2 |
| Hydrocortisone Hemisuccinate Anhydrous | None of these genes | Phase 2 |
| Idelalisib | None of these genes | Phase 2 |
| Ifosfamide | None of these genes | Phase 2 |
| Imatinib | None of these genes | Phase 2 |
| Imetelstat | None of these genes | Phase 2 |
| Incomplete Freund'S Adjuvant | None of these genes | Phase 2 |
| Indisulam | None of these genes | Phase 2 |
| Inecalcitol | None of these genes | Phase 2 |
| Interferon Gamma-1b | None of these genes | Phase 2 |
| Interleukin 15, Recombinant Non-Glycosylated | None of these genes | Phase 2 |
| Ipilimumab | None of these genes | Phase 2 |
| Isatuximab | None of these genes | Phase 2 |
| Isotretinoin | None of these genes | Phase 2 |
| Itraconazole | None of these genes | Phase 2 |
| Ixazomib | None of these genes | Phase 2 |
| Lestaurtinib | None of these genes | Phase 2 |
| Leuprolide | None of these genes | Phase 2 |
| Lirilumab | None of these genes | Phase 2 |
| Metformin | None of these genes | Phase 2 |
| Mk-2206 | None of these genes | Phase 2 |
| Mocetinostat | None of these genes | Phase 2 |
| Molibresib | None of these genes | Phase 2 |
| Monalizumab | None of these genes | Phase 2 |
| Motixafortide | None of these genes | Phase 2 |
| Nerofe | None of these genes | Phase 2 |
| Nilotinib | None of these genes | Phase 2 |
| Nintedanib | None of these genes | Phase 2 |
| Nogapendekin Alfa | None of these genes | Phase 2 |
| Obatoclax | None of these genes | Phase 2 |
| Olaparib | None of these genes | Phase 2 |
| Ombipepimut-S | None of these genes | Phase 2 |
| Pacritinib | None of these genes | Phase 2 |
| Pazopanib | None of these genes | Phase 2 |
| Pegargiminase | None of these genes | Phase 2 |
| Pegaspargase | None of these genes | Phase 2 |
| Peginterferon Alfa-2b | None of these genes | Phase 2 |
| Pembrolizumab | None of these genes | Phase 2 |
| Perifosine | None of these genes | Phase 2 |
| Phenylbutanoic Acid | None of these genes | Phase 2 |
| Pimasertib | None of these genes | Phase 2 |
| Pioglitazone | None of these genes | Phase 2 |
| Plerixafor | None of these genes | Phase 2 |
| Pomalidomide | None of these genes | Phase 2 |
| Ponatinib | None of these genes | Phase 2 |
| Pravastatin | None of these genes | Phase 2 |
| Prednisolone | None of these genes | Phase 2 |
| Prednisone | None of these genes | Phase 2 |
| Prexigebersen | None of these genes | Phase 2 |
| Pyronaridine | None of these genes | Phase 2 |
| Rafutrombopag | None of these genes | Phase 2 |
| Recombinant Human Interleukin-15 | None of these genes | Phase 2 |
| Relatlimab | None of these genes | Phase 2 |
| Ribavirin | None of these genes | Phase 2 |
| Ridaforolimus | None of these genes | Phase 2 |
| Romidepsin | None of these genes | Phase 2 |
| Ruxolitinib | None of these genes | Phase 2 |
| Sabatolimab | None of these genes | Phase 2 |
| Salsalate | None of these genes | Phase 2 |
| Sch-900776 | None of these genes | Phase 2 |
| Sel-120 Free Base | None of these genes | Phase 2 |
| Selumetinib | None of these genes | Phase 2 |
| Sephb4-Hsa | None of these genes | Phase 2 |
| Sodium Stibogluconate | None of these genes | Phase 2 |
| Sonrotoclax | None of these genes | Phase 2 |
| Succimer | None of these genes | Phase 2 |
| Sulindac | None of these genes | Phase 2 |
| Sunitinib | None of these genes | Phase 2 |
| Tamibarotene | None of these genes | Phase 2 |
| Temozolomide | None of these genes | Phase 2 |
| Temsirolimus | None of these genes | Phase 2 |
| Tetradecanoyl Phorbol Acetate | None of these genes | Phase 2 |
| Thalidomide | None of these genes | Phase 2 |
| Tislelizumab | None of these genes | Phase 2 |
| Topotecan | None of these genes | Phase 2 |
| Tosedostat | None of these genes | Phase 2 |
| Trametinib | None of these genes | Phase 2 |
| Trastuzumab | None of these genes | Phase 2 |
| Treosulfan | None of these genes | Phase 2 |
| Troculeucel | None of these genes | Phase 2 |
| Troxacitabine | None of these genes | Phase 2 |
| Uprosertib | None of these genes | Phase 2 |
| Valproic Acid | None of these genes | Phase 2 |
| Vandetanib | None of these genes | Phase 2 |
| Vatalanib | None of these genes | Phase 2 |
| Veliparib | None of these genes | Phase 2 |
| Vemurafenib | None of these genes | Phase 2 |
| Vibecotamab | None of these genes | Phase 2 |
| Vinblastine | None of these genes | Phase 2 |
| Vincristine | None of these genes | Phase 2 |
| Vismodegib | None of these genes | Phase 2 |
| Volasertib | None of these genes | Phase 2 |
| Xl-999 | None of these genes | Phase 2 |
| Zedenoleucel | None of these genes | Phase 2 |
| Zeprumetostat | None of these genes | Phase 2 |
| 8-Chloroadenosine | None of these genes | Phase 1/2 |
| Ab-8939 | None of these genes | Phase 1/2 |
| Acadesine | None of these genes | Phase 1/2 |
| Akn-028 | None of these genes | Phase 1/2 |
| Alrizomadlin | TP53 | Phase 1/2 |
| Asciminib | None of these genes | Phase 1/2 |
| At-9283 | None of these genes | Phase 1/2 |
| Atezolizumab | None of these genes | Phase 1/2 |
| Atorvastatin | None of these genes | Phase 1/2 |
| Avelumab | None of these genes | Phase 1/2 |
| Azd-5153 | None of these genes | Phase 1/2 |
| Azd-5991 | None of these genes | Phase 1/2 |
| Azenosertib | None of these genes | Phase 1/2 |
| Beroterkib Anhydrous | None of these genes | Phase 1/2 |
| Bexmarilimab | None of these genes | Phase 1/2 |
| Binimetinib | None of these genes | Phase 1/2 |
| Birabresib | None of these genes | Phase 1/2 |
| Birinapant | None of these genes | Phase 1/2 |
| Bn-104 | None of these genes | Phase 1/2 |
| Bomedemstat | None of these genes | Phase 1/2 |
| Brentuximab Vedotin | None of these genes | Phase 1/2 |
| Brequinar | None of these genes | Phase 1/2 |
| Ciprofloxacin | None of these genes | Phase 1/2 |
| Cyc-065 | None of these genes | Phase 1/2 |
| Daclizumab | None of these genes | Phase 1/2 |
| Digoxin | None of these genes | Phase 1/2 |
| Dordaviprone | None of these genes | Phase 1/2 |
| Dubermatinib | None of these genes | Phase 1/2 |
| E-6201 | None of these genes | Phase 1/2 |
| Eltanexor | None of these genes | Phase 1/2 |
| Emavusertib | None of these genes | Phase 1/2 |
| Enzomenib | None of these genes | Phase 1/2 |
| Erzotabart | None of these genes | Phase 1/2 |
| Filanesib | None of these genes | Phase 1/2 |
| Flysyn | None of these genes | Phase 1/2 |
| Fosciclopirox | None of these genes | Phase 1/2 |
| Furosemide | None of these genes | Phase 1/2 |
| Ganetespib | None of these genes | Phase 1/2 |
| Go-203-2c | None of these genes | Phase 1/2 |
| Granaticin B | None of these genes | Phase 1/2 |
| Ibi-188 | None of these genes | Phase 1/2 |
| Incb-059872 | None of these genes | Phase 1/2 |
| Interleukin-7 | None of these genes | Phase 1/2 |
| Ivuxolimab | None of these genes | Phase 1/2 |
| Kb-004 | None of these genes | Phase 1/2 |
| Lanraplenib | None of these genes | Phase 1/2 |
| Lemzoparlimab | None of these genes | Phase 1/2 |
| Lovastatin | None of these genes | Phase 1/2 |
| Luveltamab Tazevibulin | None of these genes | Phase 1/2 |
| Melk Inhibitor | None of these genes | Phase 1/2 |
| Mercaptopurine Anhydrous | None of these genes | Phase 1/2 |
| Midazolam | None of these genes | Phase 1/2 |
| Mik-665 | None of these genes | Phase 1/2 |
| Milademetan | None of these genes | Phase 1/2 |
| Mivavotinib | None of these genes | Phase 1/2 |
| Mobinitinib | None of these genes | Phase 1/2 |
| Momelotinib | None of these genes | Phase 1/2 |
| Mrx-2843 | None of these genes | Phase 1/2 |
| Muromonab-Cd3 | None of these genes | Phase 1/2 |
| Navtemadlin | TP53 | Phase 1/2 |
| Nefextinib | None of these genes | Phase 1/2 |
| Nidanilimab | None of these genes | Phase 1/2 |
| Ocifisertib | None of these genes | Phase 1/2 |
| Octanoic Acid | None of these genes | Phase 1/2 |
| Onvansertib | None of these genes | Phase 1/2 |
| Oxaliplatin | None of these genes | Phase 1/2 |
| Oxi-4503 | None of these genes | Phase 1/2 |
| Palbociclib | None of these genes | Phase 1/2 |
| Palifermin | None of these genes | Phase 1/2 |
| Pelcitoclax | None of these genes | Phase 1/2 |
| Pemrametostat | None of these genes | Phase 1/2 |
| Pexidartinib | None of these genes | Phase 1/2 |
| Phorbol Myristate Acetate | None of these genes | Phase 1/2 |
| Pinometostat | None of these genes | Phase 1/2 |
| Pixantrone | None of these genes | Phase 1/2 |
| Plitidepsin | None of these genes | Phase 1/2 |
| Posaconazole | None of these genes | Phase 1/2 |
| Pr-104 | None of these genes | Phase 1/2 |
| Pri-724 | None of these genes | Phase 1/2 |
| Rimiducid | None of these genes | Phase 1/2 |
| Rogocekib | None of these genes | Phase 1/2 |
| Safimestomig | None of these genes | Phase 1/2 |
| Samalizumab | None of these genes | Phase 1/2 |
| Semaxanib | None of these genes | Phase 1/2 |
| Siremadlin | TP53 | Phase 1/2 |
| Sjg-136 | None of these genes | Phase 1/2 |
| Spironolactone | None of these genes | Phase 1/2 |
| Sulfasalazine | None of these genes | Phase 1/2 |
| Talazoparib | None of these genes | Phase 1/2 |
| Tamnorzatinib | None of these genes | Phase 1/2 |
| Tandutinib | None of these genes | Phase 1/2 |
| Timdarpacept | None of these genes | Phase 1/2 |
| Tranylcypromine | None of these genes | Phase 1/2 |
| Tuspetinib | None of these genes | Phase 1/2 |
| Ulixertinib | None of these genes | Phase 1/2 |
| Ulocuplumab | None of these genes | Phase 1/2 |
| Vob-560 | None of these genes | Phase 1/2 |
| Abbv-744 | None of these genes | Phase 1 |
| Ags62p1 | None of these genes | Phase 1 |
| Alpelisib | None of these genes | Phase 1 |
| Amg553 | None of these genes | Phase 1 |
| Amg-900 | None of these genes | Phase 1 |
| Amv-564 | None of these genes | Phase 1 |
| Anzurstobart | None of these genes | Phase 1 |
| Aplitabart | None of these genes | Phase 1 |
| Apolizumab | None of these genes | Phase 1 |
| Apto-253 | None of these genes | Phase 1 |
| Apvo-436 | None of these genes | Phase 1 |
| Ar-42 | None of these genes | Phase 1 |
| Astx-660 | None of these genes | Phase 1 |
| Autologous Cord Blood | None of these genes | Phase 1 |
| Ave-9633 | None of these genes | Phase 1 |
| Axatilimab | None of these genes | Phase 1 |
| Azd-1208 | None of these genes | Phase 1 |
| Azd-4877 | None of these genes | Phase 1 |
| Basiliximab | None of these genes | Phase 1 |
| Bay1436032 | None of these genes | Phase 1 |
| Bosutinib | None of these genes | Phase 1 |
| Btx-A51 | None of these genes | Phase 1 |
| Cabozantinib | None of these genes | Phase 1 |
| Caffeine | None of these genes | Phase 1 |
| Calcium | None of these genes | Phase 1 |
| Camibirstat | None of these genes | Phase 1 |
| Carfilzomib | None of these genes | Phase 1 |
| Cc-401 | None of these genes | Phase 1 |
| Cemiplimab | None of these genes | Phase 1 |
| Ceramide | None of these genes | Phase 1 |
| Cirtuvivint | None of these genes | Phase 1 |
| Cobimetinib | None of these genes | Phase 1 |
| Csl-360 | None of these genes | Phase 1 |
| Dactolisib | None of these genes | Phase 1 |
| Danvatirsen | None of these genes | Phase 1 |
| Dcll-9718s | None of these genes | Phase 1 |
| Defactinib | None of these genes | Phase 1 |
| Defosbarasertib | None of these genes | Phase 1 |
| Dextromethorphan | None of these genes | Phase 1 |
| Dovitinib | None of these genes | Phase 1 |
| Doxecitine | None of these genes | Phase 1 |
| Dvx-201 | None of these genes | Phase 1 |
| Eftozanermin Alfa | None of these genes | Phase 1 |
| Eganelisib | None of these genes | Phase 1 |
| Elesclomol | None of these genes | Phase 1 |
| Elotuzumab | None of these genes | Phase 1 |
| Eluvixtamab | None of these genes | Phase 1 |
| Emirodatamab | None of these genes | Phase 1 |
| Emvododstat | None of these genes | Phase 1 |
| Entrectinib | None of these genes | Phase 1 |
| Epacadostat | None of these genes | Phase 1 |
| Eragidomide | None of these genes | Phase 1 |
| Etoposide Phosphate | None of these genes | Phase 1 |
| Evorpacept | None of these genes | Phase 1 |
| Exatecan | None of these genes | Phase 1 |
| F16il2 | None of these genes | Phase 1 |
| Fenretinide | None of these genes | Phase 1 |
| Ff-10101 | None of these genes | Phase 1 |
| Fluorouracil | None of these genes | Phase 1 |
| Flurbiprofen | None of these genes | Phase 1 |
| Fosmanogepix | None of these genes | Phase 1 |
| Fulvestrant | None of these genes | Phase 1 |
| Ganciclovir | None of these genes | Phase 1 |
| Gentulizumab | None of these genes | Phase 1 |
| Gnkg-168 | None of these genes | Phase 1 |
| Gsk2879552 | None of these genes | Phase 1 |
| H3b-8800 | None of these genes | Phase 1 |
| Hiltonol | None of these genes | Phase 1 |
| Hydroxychloroquine | None of these genes | Phase 1 |
| Iacs-010759 | None of these genes | Phase 1 |
| Iadademstat | None of these genes | Phase 1 |
| Icovamenib | None of these genes | Phase 1 |
| Idh305 | None of these genes | Phase 1 |
| Ign-523 | None of these genes | Phase 1 |
| Imc-Eb10 | None of these genes | Phase 1 |
| Imgn-779 | None of these genes | Phase 1 |
| Indigo | None of these genes | Phase 1 |
| Indoximod | None of these genes | Phase 1 |
| Interleukin-12 Human Recombinant | None of these genes | Phase 1 |
| Iph-2101 | None of these genes | Phase 1 |
| Irinotecan | None of these genes | Phase 1 |
| Irofulven | None of these genes | Phase 1 |
| Jnj-64264681 | None of these genes | Phase 1 |
| Kw-2449 | None of these genes | Phase 1 |
| Leucovorin | None of these genes | Phase 1 |
| Lgh-447 | None of these genes | Phase 1 |
| Lithium Carbonate | None of these genes | Phase 1 |
| Litronesib | None of these genes | Phase 1 |
| Luxeptinib | None of these genes | Phase 1 |
| Ly-2874455 | None of these genes | Phase 1 |
| Maplirpacept | None of these genes | Phase 1 |
| Medi-7247 | None of these genes | Phase 1 |
| Merestinib | None of these genes | Phase 1 |
| Mezigdomide | None of these genes | Phase 1 |
| Minnelide Free Salt | None of these genes | Phase 1 |
| Mitomycin | None of these genes | Phase 1 |
| Mivebresib | None of these genes | Phase 1 |
| Navitoclax | None of these genes | Phase 1 |
| Nedisertib | None of these genes | Phase 1 |
| Niclosamide | None of these genes | Phase 1 |
| Ningetinib | None of these genes | Phase 1 |
| Nrx195183 | None of these genes | Phase 1 |
| Obinutuzumab | None of these genes | Phase 1 |
| Oblimersen | None of these genes | Phase 1 |
| Olverembatinib | None of these genes | Phase 1 |
| Omeprazole | None of these genes | Phase 1 |
| Onametostat | None of these genes | Phase 1 |
| Paclitaxel | None of these genes | Phase 1 |
| Padnarsertib | None of these genes | Phase 1 |
| Pasifolate Exatecan | None of these genes | Phase 1 |
| Pegzilarginase | None of these genes | Phase 1 |
| Pemigatinib | None of these genes | Phase 1 |
| Pemvidutide | None of these genes | Phase 1 |
| Pf-06747143 | None of these genes | Phase 1 |
| Phi-101 | None of these genes | Phase 1 |
| Pitavastatin | None of these genes | Phase 1 |
| Plx-51107 | None of these genes | Phase 1 |
| Prexasertib | None of these genes | Phase 1 |
| Pulrodemstat | None of these genes | Phase 1 |
| Rebastinib | None of these genes | Phase 1 |
| Rebeccamycin | None of these genes | Phase 1 |
| Regorafenib | None of these genes | Phase 1 |
| Rezatapopt | None of these genes | Phase 1 |
| Rezetamig | None of these genes | Phase 1 |
| Ro-5045337 | None of these genes | Phase 1 |
| Ro-5429083 | None of these genes | Phase 1 |
| Ro-6870810 | None of these genes | Phase 1 |
| Romiplostim | None of these genes | Phase 1 |
| Rosuvastatin | None of these genes | Phase 1 |
| Safimaltib | None of these genes | Phase 1 |
| Sertraline | None of these genes | Phase 1 |
| Sgn-Cd123a | None of these genes | Phase 1 |
| Siltuximab | None of these genes | Phase 1 |
| Sodium Iodide | None of these genes | Phase 1 |
| Sodium Salicylate | None of these genes | Phase 1 |
| Sonidegib | None of these genes | Phase 1 |
| Sovleplenib | None of these genes | Phase 1 |
| Spartalizumab | None of these genes | Phase 1 |
| Sulanemadlin | None of these genes | Phase 1 |
| Tak-243 | None of these genes | Phase 1 |
| Tanespimycin | None of these genes | Phase 1 |
| Taniraleucel | None of these genes | Phase 1 |
| Tapotoclax | None of these genes | Phase 1 |
| Tas-1553 | None of these genes | Phase 1 |
| Tasisulam | None of these genes | Phase 1 |
| Tazemetostat | None of these genes | Phase 1 |
| Tefinostat | None of these genes | Phase 1 |
| Tegavivint | None of these genes | Phase 1 |
| Telaglenastat | None of these genes | Phase 1 |
| Temuterkib | None of these genes | Phase 1 |
| Tetrahydrouridine | None of these genes | Phase 1 |
| Thioridazine | None of these genes | Phase 1 |
| Tigecycline | None of these genes | Phase 1 |
| Tirbanibulin | None of these genes | Phase 1 |
| Tocilizumab | None of these genes | Phase 1 |
| Tomivosertib | None of these genes | Phase 1 |
| Trebananib | None of these genes | Phase 1 |
| Ucn-01 | None of these genes | Phase 1 |
| Valemetostat | None of these genes | Phase 1 |
| Voruciclib | None of these genes | Phase 1 |
| Vs-4718 | None of these genes | Phase 1 |
| Xevinapant | None of these genes | Phase 1 |
| Yttrium | None of these genes | Phase 1 |
| Zelenirstat | None of these genes | Phase 1 |
| Atovaquone | None of these genes | Early phase 1 |
| Emerfetamab | None of these genes | Early phase 1 |
| Novaferon | None of these genes | Early phase 1 |
| Ropeginterferon Alfa-2b | None of these genes | Early phase 1 |
| Sodium Bicarbonate | None of these genes | Early phase 1 |
| Toripalimab | None of these genes | Early phase 1 |
| Avitotamig | None of these genes | Unknown |
| Hma | None of these genes | Unknown |
| Metronidazole | None of these genes | Unknown |
| Niraparib | None of these genes | Unknown |
| Rucaparib | None of these genes | Unknown |
| Voriconazole | None of these genes | Unknown |
The drug data is ChEMBL's, under CC BY-SA 3.0, and came through Open Targets release 26.09.