Human disease
type 2 diabetes mellitus
Mondo defines it as: “A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity.”
4 disease groups in OMIA reach this disease, through OMIA's own Mondo link or its OMIM numbers. The page shows the chain. It does not say whether an animal is a model of this disease.
Animal diseases
By natural-model score for this disease, highest first. The score says how complete and how well supported each chain is, by stated rules. How the score works.
| OMIA group | Name | Found by | Species | The chain reached | Score |
|---|---|---|---|---|---|
| 284 | Diabetes mellitus, type 2 | Both routes | 7 | Drug |
89.4
|
| 279 | Diabetes mellitus | OMIA's OMIM numbers | 11 | Target evidence |
60.7
|
| 3069 | Diabetes mellitus, PAX4-related | OMIA's OMIM numbers | 1 | Target evidence |
55.7
|
| 2552 | Pancreatic agenesis, PDX1-related | OMIA's OMIM numbers | 3 | Target evidence |
51.1
|
Human genes
Each human gene of these disease groups that Open Targets links to this disease.
| Human gene | Score | Evidence |
|---|---|---|
| PAX4 | 0.74 | 209 |
| GIPR | 0.70 | 406 |
| IRS2 | 0.61 | 313 |
| PDX1 | 0.60 | 519 |
| INS | 0.59 | 59,656 |
Drugs tested for this disease
Each ChEMBL drug that has been tested for this disease, and the human genes above it acts on, if any. Open Targets gives some drugs, such as most enzyme replacement therapies, no target gene.
| Drug | Acts on | Latest stage for this disease |
|---|---|---|
| Acarbose | None of these genes | Approved |
| Albiglutide | None of these genes | Approved |
| Alogliptin | None of these genes | Approved |
| Anagliptin | None of these genes | Approved |
| Bexagliflozin | None of these genes | Approved |
| Biotin | None of these genes | Approved |
| Bromocriptine | None of these genes | Approved |
| Canagliflozin Anhydrous | None of these genes | Approved |
| Cetilistat | None of these genes | Approved |
| Chlorpropamide | None of these genes | Approved |
| Colesevelam | None of these genes | Approved |
| Cyanocobalamin | None of these genes | Approved |
| Dapagliflozin | None of these genes | Approved |
| Dulaglutide | None of these genes | Approved |
| Empagliflozin | None of these genes | Approved |
| Ertugliflozin | None of these genes | Approved |
| Exenatide | None of these genes | Approved |
| Fenofibrate | None of these genes | Approved |
| Fenofibric Acid | None of these genes | Approved |
| Finerenone | None of these genes | Approved |
| Folic Acid | None of these genes | Approved |
| Glimepiride | None of these genes | Approved |
| Glipizide | None of these genes | Approved |
| Glisoxepide | None of these genes | Approved |
| Glyburide | None of these genes | Approved |
| Insulin Degludec | None of these genes | Approved |
| Insulin Detemir | None of these genes | Approved |
| Insulin Glargine | None of these genes | Approved |
| Insulin Human | None of these genes | Approved |
| Insulin Icodec | None of these genes | Approved |
| Ipragliflozin L-Proline | None of these genes | Approved |
| Irbesartan | None of these genes | Approved |
| Linagliptin | None of these genes | Approved |
| Liraglutide | None of these genes | Approved |
| Lixisenatide | None of these genes | Approved |
| Lobeglitazone | None of these genes | Approved |
| Metformin | None of these genes | Approved |
| Miglitol | None of these genes | Approved |
| Mitiglinide Calcium Dihydrate | None of these genes | Approved |
| Nateglinide | None of these genes | Approved |
| Omarigliptin | None of these genes | Approved |
| Omega-3-Acid Ethyl Esters | None of these genes | Approved |
| Pioglitazone | None of these genes | Approved |
| Pyridoxine | None of these genes | Approved |
| Repaglinide | None of these genes | Approved |
| Rosiglitazone | None of these genes | Approved |
| Saxagliptin Anhydrous | None of these genes | Approved |
| Semaglutide | None of these genes | Approved |
| Simvastatin | None of these genes | Approved |
| Sitagliptin | None of these genes | Approved |
| Sotagliflozin | None of these genes | Approved |
| Ticagrelor | None of these genes | Approved |
| Tirzepatide | GIPR | Approved |
| Tofogliflozin Anhydrous | None of these genes | Approved |
| Tolazamide | None of these genes | Approved |
| Tolbutamide | None of these genes | Approved |
| Trelagliptin | None of these genes | Approved |
| Tyrosine | None of these genes | Approved |
| Vildagliptin | None of these genes | Approved |
| Voglibose | None of these genes | Approved |
| Luseogliflozin | None of these genes | Awaiting approval |
| Acetylcarnitine | None of these genes | Phase 3 |
| Aleglitazar | None of these genes | Phase 3 |
| Alirocumab | None of these genes | Phase 3 |
| Allopurinol | None of these genes | Phase 3 |
| Amlodipine | None of these genes | Phase 3 |
| Amoxicillin | None of these genes | Phase 3 |
| Aspirin | None of these genes | Phase 3 |
| Atorvastatin | None of these genes | Phase 3 |
| Avexitide | None of these genes | Phase 3 |
| Azilsartan | None of these genes | Phase 3 |
| Azilsartan Medoxomil | None of these genes | Phase 3 |
| Balaglitazone | None of these genes | Phase 3 |
| Berberine | None of these genes | Phase 3 |
| Berberine Ursodeoxycholate | None of these genes | Phase 3 |
| Bezisterim | None of these genes | Phase 3 |
| Bifidobacterium Spp. | None of these genes | Phase 3 |
| Biguanide | None of these genes | Phase 3 |
| Bupropion | None of these genes | Phase 3 |
| Cabergoline | None of these genes | Phase 3 |
| Cagrilintide | None of these genes | Phase 3 |
| Canakinumab | None of these genes | Phase 3 |
| Chiglitazar | None of these genes | Phase 3 |
| Cholecalciferol | None of these genes | Phase 3 |
| Chromium | None of these genes | Phase 3 |
| Cinnamon | None of these genes | Phase 3 |
| Clindamycin | None of these genes | Phase 3 |
| Clonidine | None of these genes | Phase 3 |
| Cofrogliptin | None of these genes | Phase 3 |
| Colchicine | None of these genes | Phase 3 |
| Dbpr-108 | None of these genes | Phase 3 |
| Dextrose | None of these genes | Phase 3 |
| Diacerein | None of these genes | Phase 3 |
| Dorzagliatin | None of these genes | Phase 3 |
| Doxycycline Anhydrous | None of these genes | Phase 3 |
| Dutogliptin | None of these genes | Phase 3 |
| Ecnoglutide | None of these genes | Phase 3 |
| Efpeglenatide | None of these genes | Phase 3 |
| Efsubaglutide Alfa | None of these genes | Phase 3 |
| Eloralintide | None of these genes | Phase 3 |
| Enalapril | None of these genes | Phase 3 |
| Enavogliflozin | None of these genes | Phase 3 |
| Eplerenone | None of these genes | Phase 3 |
| Ergocalciferol | None of these genes | Phase 3 |
| Esomeprazole | None of these genes | Phase 3 |
| Evogliptin | None of these genes | Phase 3 |
| Evolocumab | None of these genes | Phase 3 |
| Ezetimibe | None of these genes | Phase 3 |
| Fasiglifam | None of these genes | Phase 3 |
| Ferric Carboxymaltose | None of these genes | Phase 3 |
| Fexofenadine | None of these genes | Phase 3 |
| Gemigliptin | None of these genes | Phase 3 |
| Gevokizumab | None of these genes | Phase 3 |
| Gliclazide | None of these genes | Phase 3 |
| Glucagon | None of these genes | Phase 3 |
| Gosogliptin | None of these genes | Phase 3 |
| Gulgafafusp Alfa | None of these genes | Phase 3 |
| Henagliflozin | None of these genes | Phase 3 |
| Icodextrin | None of these genes | Phase 3 |
| Icosapent | None of these genes | Phase 3 |
| Imidapril | None of these genes | Phase 3 |
| Imiglitazar | None of these genes | Phase 3 |
| Inosine | None of these genes | Phase 3 |
| Insulin Aspart | None of these genes | Phase 3 |
| Insulin Efsitora Alfa | None of these genes | Phase 3 |
| Insulin Glulisine | None of these genes | Phase 3 |
| Insulin Human, Isophane | None of these genes | Phase 3 |
| Insulin Lispro | None of these genes | Phase 3 |
| Insulin Peglispro | None of these genes | Phase 3 |
| Insulin Susp Isophane Beef | None of these genes | Phase 3 |
| Ipragliflozin | None of these genes | Phase 3 |
| Ivabradine | None of these genes | Phase 3 |
| Jt-001 | None of these genes | Phase 3 |
| Lapaquistat Acetate | None of these genes | Phase 3 |
| Laropiprant | None of these genes | Phase 3 |
| Lidocaine | None of these genes | Phase 3 |
| Lipoic Acid, Alpha | None of these genes | Phase 3 |
| Lorcaserin | None of these genes | Phase 3 |
| Losartan | None of these genes | Phase 3 |
| Maridebart Cafraglutide | None of these genes | Phase 3 |
| Mazdutide | None of these genes | Phase 3 |
| Mecasermin | None of these genes | Phase 3 |
| Melatonin | None of these genes | Phase 3 |
| Menaquinone 6 | None of these genes | Phase 3 |
| Metformin Glycinate | None of these genes | Phase 3 |
| Metronidazole | None of these genes | Phase 3 |
| Mifepristone | None of these genes | Phase 3 |
| Mitiglinide | None of these genes | Phase 3 |
| Mk-0767 | None of these genes | Phase 3 |
| Muraglitazar | None of these genes | Phase 3 |
| Naltrexone | None of these genes | Phase 3 |
| Niacin | None of these genes | Phase 3 |
| Niacinamide | None of these genes | Phase 3 |
| Nicorandil | None of these genes | Phase 3 |
| Obicetrapib | None of these genes | Phase 3 |
| Orforglipron | None of these genes | Phase 3 |
| Otenabant | None of these genes | Phase 3 |
| Panobinostat | None of these genes | Phase 3 |
| Pantoprazole | None of these genes | Phase 3 |
| Paroxetine | None of these genes | Phase 3 |
| Pegloxenatide | None of these genes | Phase 3 |
| Perindopril | None of these genes | Phase 3 |
| Phentermine | None of these genes | Phase 3 |
| Physioneal | None of these genes | Phase 3 |
| Pitavastatin | None of these genes | Phase 3 |
| Pramlintide | None of these genes | Phase 3 |
| Ramipril | None of these genes | Phase 3 |
| Ranolazine | None of these genes | Phase 3 |
| Relacorilant | None of these genes | Phase 3 |
| Retagliptin | None of these genes | Phase 3 |
| Retatrutide | GIPR | Phase 3 |
| Riboflavin | None of these genes | Phase 3 |
| Rilparencel | None of these genes | Phase 3 |
| Rimonabant | None of these genes | Phase 3 |
| Rivaroxaban | None of these genes | Phase 3 |
| Rivoglitazone | None of these genes | Phase 3 |
| Roflumilast | None of these genes | Phase 3 |
| Rosuvastatin | None of these genes | Phase 3 |
| Sacubitril | None of these genes | Phase 3 |
| Sildenafil | None of these genes | Phase 3 |
| Sodium Fluoride | None of these genes | Phase 3 |
| Somatropin | None of these genes | Phase 3 |
| Spironolactone | None of these genes | Phase 3 |
| Succinic Acid | None of these genes | Phase 3 |
| Sulodexide | None of these genes | Phase 3 |
| Survodutide | None of these genes | Phase 3 |
| Tagatose | None of these genes | Phase 3 |
| Taranabant | None of these genes | Phase 3 |
| Taspoglutide | None of these genes | Phase 3 |
| Taurursodiol | None of these genes | Phase 3 |
| Telmisartan | None of these genes | Phase 3 |
| Teneligliptin | None of these genes | Phase 3 |
| Tesaglitazar | None of these genes | Phase 3 |
| Testosterone | None of these genes | Phase 3 |
| Testosterone Undecanoate | None of these genes | Phase 3 |
| Thiazolidinedione | None of these genes | Phase 3 |
| Topiramate | None of these genes | Phase 3 |
| Tributyrin | None of these genes | Phase 3 |
| Triclosan | None of these genes | Phase 3 |
| Urea | None of these genes | Phase 3 |
| Ursodiol | None of these genes | Phase 3 |
| Valsartan | None of these genes | Phase 3 |
| Visepegenatide | None of these genes | Phase 3 |
| Acipimox | None of these genes | Phase 2/3 |
| Aloe | None of these genes | Phase 2/3 |
| Apabetalone | None of these genes | Phase 2/3 |
| Arhalofenate | None of these genes | Phase 2/3 |
| Bemiparin | None of these genes | Phase 2/3 |
| Bevacizumab | None of these genes | Phase 2/3 |
| Calcitriol | None of these genes | Phase 2/3 |
| Denagliptin | None of these genes | Phase 2/3 |
| Dobesilic Acid | None of these genes | Phase 2/3 |
| Dorzolamide | None of these genes | Phase 2/3 |
| Glucosamine | None of these genes | Phase 2/3 |
| Ibipinabant | None of these genes | Phase 2/3 |
| Indocyanine Green Acid Form | None of these genes | Phase 2/3 |
| Insulin Tregopil | None of these genes | Phase 2/3 |
| Levoketoconazole | None of these genes | Phase 2/3 |
| Mecobalamin | None of these genes | Phase 2/3 |
| Metoprolol | None of these genes | Phase 2/3 |
| Nebivolol | None of these genes | Phase 2/3 |
| Orgotein | None of these genes | Phase 2/3 |
| Pemoline | None of these genes | Phase 2/3 |
| Propofol | None of these genes | Phase 2/3 |
| Salsalate | None of these genes | Phase 2/3 |
| Succinobucol | None of these genes | Phase 2/3 |
| Timolol | None of these genes | Phase 2/3 |
| Vitamin E | None of these genes | Phase 2/3 |
| Acetylcysteine | None of these genes | Phase 2 |
| Aclimostat | None of these genes | Phase 2 |
| Adomeglivant | None of these genes | Phase 2 |
| Alcohol | None of these genes | Phase 2 |
| Aldafermin | None of these genes | Phase 2 |
| Aleniglipron | None of these genes | Phase 2 |
| Aliskiren | None of these genes | Phase 2 |
| Alt-2074 | None of these genes | Phase 2 |
| Alvelestat | None of these genes | Phase 2 |
| Amantadine | None of these genes | Phase 2 |
| Amg-108 | None of these genes | Phase 2 |
| Amlexanox | None of these genes | Phase 2 |
| Ampelopsin | None of these genes | Phase 2 |
| Anakinra | None of these genes | Phase 2 |
| Anastrozole | None of these genes | Phase 2 |
| Apelin | None of these genes | Phase 2 |
| Ascorbic Acid | None of these genes | Phase 2 |
| Aspirin Trelamine | None of these genes | Phase 2 |
| Atazanavir | None of these genes | Phase 2 |
| Atigliflozin | None of these genes | Phase 2 |
| Atrasentan | None of these genes | Phase 2 |
| Atx08-001 | None of these genes | Phase 2 |
| Azd-1656 | None of these genes | Phase 2 |
| Azd-4017 | None of these genes | Phase 2 |
| Bardoxolone Methyl | None of these genes | Phase 2 |
| Bazedoxifene | None of these genes | Phase 2 |
| Beloranib | None of these genes | Phase 2 |
| Bempedoic Acid | None of these genes | Phase 2 |
| Benfluorex | None of these genes | Phase 2 |
| Bermekimab | None of these genes | Phase 2 |
| Besigliptin Tosylate | None of these genes | Phase 2 |
| Bgp-15 | None of these genes | Phase 2 |
| Bi-187004 | None of these genes | Phase 2 |
| Bimagrumab | None of these genes | Phase 2 |
| Bisegliptin | None of these genes | Phase 2 |
| Bms-741672 | None of these genes | Phase 2 |
| Bms-770767 | None of these genes | Phase 2 |
| Bms-823778 Free Base | None of these genes | Phase 2 |
| Bosentan | None of these genes | Phase 2 |
| Cadisegliatin | None of these genes | Phase 2 |
| Camicinal | None of these genes | Phase 2 |
| Cannabidiol | None of these genes | Phase 2 |
| Ce-326597 | None of these genes | Phase 2 |
| Celecoxib | None of these genes | Phase 2 |
| Cenicriviroc | None of these genes | Phase 2 |
| Chlorhexidine | None of these genes | Phase 2 |
| Cibinetide | None of these genes | Phase 2 |
| Clofutriben | None of these genes | Phase 2 |
| Clopidogrel | None of these genes | Phase 2 |
| Colestilan Chloride | None of these genes | Phase 2 |
| Cotadutide | None of these genes | Phase 2 |
| Cp-778875 | None of these genes | Phase 2 |
| Daglutril | None of these genes | Phase 2 |
| Danuglipron | None of these genes | Phase 2 |
| Dapansutrile | None of these genes | Phase 2 |
| Denosumab | None of these genes | Phase 2 |
| Dextromethorphan | None of these genes | Phase 2 |
| Diazoxide | None of these genes | Phase 2 |
| Digoxin | None of these genes | Phase 2 |
| Doconexent | None of these genes | Phase 2 |
| Donepezil | None of these genes | Phase 2 |
| Edaglitazone | None of these genes | Phase 2 |
| Efinopegdutide | None of these genes | Phase 2 |
| Elafibranor | None of these genes | Phase 2 |
| Enclomiphene | None of these genes | Phase 2 |
| Epeleuton | None of these genes | Phase 2 |
| Epigalocatechin Gallate | None of these genes | Phase 2 |
| Eprodisate | None of these genes | Phase 2 |
| Eritoran | None of these genes | Phase 2 |
| Febuxostat | None of these genes | Phase 2 |
| Firuglipel | None of these genes | Phase 2 |
| Foralumab | None of these genes | Phase 2 |
| Froniglutide | None of these genes | Phase 2 |
| Goserelin | None of these genes | Phase 2 |
| Granotapide | None of these genes | Phase 2 |
| Gsk-1070806 | None of these genes | Phase 2 |
| Gsk-1292263 | None of these genes | Phase 2 |
| Hyaluronidase (Human Recombinant) | None of these genes | Phase 2 |
| Hydrochlorothiazide | None of these genes | Phase 2 |
| Hydroxychloroquine | None of these genes | Phase 2 |
| Icovamenib | None of these genes | Phase 2 |
| Ilacirnon | None of these genes | Phase 2 |
| Imarikiren | None of these genes | Phase 2 |
| Imeglimin | None of these genes | Phase 2 |
| Incb-13739 | None of these genes | Phase 2 |
| Indeglitazar | None of these genes | Phase 2 |
| Insulin Pork | None of these genes | Phase 2 |
| Int131 | None of these genes | Phase 2 |
| Isosteviol | None of these genes | Phase 2 |
| Jnj-41443532 | None of these genes | Phase 2 |
| Lanifibranor | None of these genes | Phase 2 |
| Leucine | None of these genes | Phase 2 |
| Levothyroxine | None of these genes | Phase 2 |
| Lgd-6972 | None of these genes | Phase 2 |
| Licogliflozin | None of these genes | Phase 2 |
| Linerixibat | None of these genes | Phase 2 |
| Lotiglipron | None of these genes | Phase 2 |
| Ly-2608204 | None of these genes | Phase 2 |
| Macupatide | None of these genes | Phase 2 |
| Mb-05032 | None of these genes | Phase 2 |
| Mb-07803 | None of these genes | Phase 2 |
| Mbx-2044 | None of these genes | Phase 2 |
| Mbx-2982 | None of these genes | Phase 2 |
| Methazolamide | None of these genes | Phase 2 |
| Mipomersen | None of these genes | Phase 2 |
| Mitoglitazone | None of these genes | Phase 2 |
| Mizacorat | None of these genes | Phase 2 |
| Mk-0533 | None of these genes | Phase 2 |
| Mk-0736 | None of these genes | Phase 2 |
| Mk-0893 | None of these genes | Phase 2 |
| Mk-0941 Free Base | None of these genes | Phase 2 |
| Mk-3577 | None of these genes | Phase 2 |
| Mk-8245 | None of these genes | Phase 2 |
| Naveglitazar | None of these genes | Phase 2 |
| Ncx-4016 | None of these genes | Phase 2 |
| Nerigliatin | None of these genes | Phase 2 |
| Nidufexor | None of these genes | Phase 2 |
| Ninerafaxstat | None of these genes | Phase 2 |
| Nisotirostide | None of these genes | Phase 2 |
| Nitazoxanide | None of these genes | Phase 2 |
| Nt-0796 | None of these genes | Phase 2 |
| Obeticholic Acid | None of these genes | Phase 2 |
| Ocaperidone | None of these genes | Phase 2 |
| Ofirnoflast | None of these genes | Phase 2 |
| Orlistat | None of these genes | Phase 2 |
| Ox Bile | None of these genes | Phase 2 |
| Oxyntomodulin | None of these genes | Phase 2 |
| Paricalcitol | None of these genes | Phase 2 |
| Pegapamodutide | None of these genes | Phase 2 |
| Pegbelfermin | None of these genes | Phase 2 |
| Pegloticase | None of these genes | Phase 2 |
| Pegsebrenatide | None of these genes | Phase 2 |
| Petrelintide | None of these genes | Phase 2 |
| Pf-04991532 | None of these genes | Phase 2 |
| Pf-05175157 | None of these genes | Phase 2 |
| Pf-06291874 | None of these genes | Phase 2 |
| Pf-06835919 | None of these genes | Phase 2 |
| Pg-102 | None of these genes | Phase 2 |
| Plozalizumab | None of these genes | Phase 2 |
| Praliciguat | None of these genes | Phase 2 |
| Prasugrel | None of these genes | Phase 2 |
| Prednisolone | None of these genes | Phase 2 |
| Propolis Wax | None of these genes | Phase 2 |
| Pyridoxal Phosphate Anhydrous | None of these genes | Phase 2 |
| Quercetin | None of these genes | Phase 2 |
| Rafabegron | None of these genes | Phase 2 |
| Relaxin | None of these genes | Phase 2 |
| Remogliflozin Etabonate | None of these genes | Phase 2 |
| Resveratrol | None of these genes | Phase 2 |
| Ro-5027838 | None of these genes | Phase 2 |
| Ruboxistaurin | None of these genes | Phase 2 |
| Sar425899 | None of these genes | Phase 2 |
| Sb-756050 | None of these genes | Phase 2 |
| Setogepram | None of these genes | Phase 2 |
| Silibinin | None of these genes | Phase 2 |
| Sinecatechins | None of these genes | Phase 2 |
| Slx-4090 | None of these genes | Phase 2 |
| Sodelglitazar | None of these genes | Phase 2 |
| Srt-2104 | None of these genes | Phase 2 |
| Sulforaphane | None of these genes | Phase 2 |
| Tadalafil | None of these genes | Phase 2 |
| Taurine | None of these genes | Phase 2 |
| Tc-6987 | None of these genes | Phase 2 |
| Tesamorelin | None of these genes | Phase 2 |
| Tesofensine | None of these genes | Phase 2 |
| Tetradecylthioacetic Acid | None of these genes | Phase 2 |
| Tetrahydrocannabivarin | None of these genes | Phase 2 |
| Thymol | None of these genes | Phase 2 |
| Tipelukast | None of these genes | Phase 2 |
| Tolimidone | None of these genes | Phase 2 |
| Triamcinolone Acetonide | None of these genes | Phase 2 |
| Tzp-102 | None of these genes | Phase 2 |
| Ubidecarenone | None of these genes | Phase 2 |
| Usistapide | None of these genes | Phase 2 |
| Verapamil | None of these genes | Phase 2 |
| Verinurad | None of these genes | Phase 2 |
| Vicadrostat | None of these genes | Phase 2 |
| Vicasinabin | None of these genes | Phase 2 |
| Vigabatrin | None of these genes | Phase 2 |
| Volanesorsen | None of these genes | Phase 2 |
| Vupanorsen | None of these genes | Phase 2 |
| Xen-D0501 | None of these genes | Phase 2 |
| Xl550 | None of these genes | Phase 2 |
| Ym-543 Free Acid | None of these genes | Phase 2 |
| Yohimbine | None of these genes | Phase 2 |
| Zanamivir | None of these genes | Phase 2 |
| Zibotentan | None of these genes | Phase 2 |
| Zinc Oxide | None of these genes | Phase 2 |
| Captopril | None of these genes | Phase 1/2 |
| Fish Oil | None of these genes | Phase 1/2 |
| Galantamine | None of these genes | Phase 1/2 |
| Hepalatide | None of these genes | Phase 1/2 |
| Ketoconazole | None of these genes | Phase 1/2 |
| Nicotinamide Riboside | None of these genes | Phase 1/2 |
| Onabotulinumtoxina | None of these genes | Phase 1/2 |
| Oxygen | None of these genes | Phase 1/2 |
| Recombinant Human Kallikrein-1 | None of these genes | Phase 1/2 |
| Rexlemestrocel-L | None of these genes | Phase 1/2 |
| Salacinol | None of these genes | Phase 1/2 |
| Taurocholic Acid | None of these genes | Phase 1/2 |
| Volagidemab | None of these genes | Phase 1/2 |
| 3-Hydroxybutyric Acid, (+/-)- | None of these genes | Phase 1 |
| Acetaminophen | None of these genes | Phase 1 |
| Acetylcholine | None of these genes | Phase 1 |
| Adp-597 | None of these genes | Phase 1 |
| Alpelisib | None of these genes | Phase 1 |
| Bethanechol | None of these genes | Phase 1 |
| Bms-686117 | None of these genes | Phase 1 |
| Bms-820132 | None of these genes | Phase 1 |
| Bms-903452 | None of these genes | Phase 1 |
| Bti-410 | None of these genes | Phase 1 |
| Buloxibutid | None of these genes | Phase 1 |
| Caffeine | None of these genes | Phase 1 |
| Chembl569766 | None of these genes | Phase 1 |
| Chromium Picolinate | None of these genes | Phase 1 |
| Clx-0921 | None of these genes | Phase 1 |
| Crotedumab | None of these genes | Phase 1 |
| Darapladib | None of these genes | Phase 1 |
| Dronabinol | None of these genes | Phase 1 |
| Drospirenone | None of these genes | Phase 1 |
| Edasalonexent | None of these genes | Phase 1 |
| Efavirenz | None of these genes | Phase 1 |
| Efruxifermin | None of these genes | Phase 1 |
| Emugrobart | None of these genes | Phase 1 |
| Englitazone | None of these genes | Phase 1 |
| Eszopiclone | None of these genes | Phase 1 |
| Ethinyl Estradiol | None of these genes | Phase 1 |
| Fazpilodemab | None of these genes | Phase 1 |
| Furosemide | None of these genes | Phase 1 |
| Ghrelin | None of these genes | Phase 1 |
| Glutamine | None of these genes | Phase 1 |
| Golocdacimab | None of these genes | Phase 1 |
| Gsk-1614235 | None of these genes | Phase 1 |
| Jtt-251 | None of these genes | Phase 1 |
| Lansoprazole | None of these genes | Phase 1 |
| Linoleic Acid | None of these genes | Phase 1 |
| Ly-2405319 | None of these genes | Phase 1 |
| Ly2881835 | None of these genes | Phase 1 |
| Medi-7219 | None of these genes | Phase 1 |
| Midazolam | None of these genes | Phase 1 |
| Mk-8666 | None of these genes | Phase 1 |
| Nomegestrol Acetate | None of these genes | Phase 1 |
| Olanzapine | None of these genes | Phase 1 |
| Olive Oil | None of these genes | Phase 1 |
| Omeprazole | None of these genes | Phase 1 |
| Ore-1001 | None of these genes | Phase 1 |
| Pamrevlumab | None of these genes | Phase 1 |
| Pemvidutide | None of these genes | Phase 1 |
| Pf-03882845 | None of these genes | Phase 1 |
| Pf-04603629 | None of these genes | Phase 1 |
| Pf-04620110 | None of these genes | Phase 1 |
| Pf-5190457 | None of these genes | Phase 1 |
| Propranolol | None of these genes | Phase 1 |
| Rebaudioside A | None of these genes | Phase 1 |
| Rongliflozin | None of these genes | Phase 1 |
| Rotavirus, Live | None of these genes | Phase 1 |
| Rotavirus, Live Attenuated | None of these genes | Phase 1 |
| Selonabant | None of these genes | Phase 1 |
| Torsemide | None of these genes | Phase 1 |
| Trodusquemine | None of these genes | Phase 1 |
| Xelaglifam | None of these genes | Phase 1 |
| Amiloride | None of these genes | Early phase 1 |
| Atropine | None of these genes | Early phase 1 |
| Ginseng, Asian | None of these genes | Early phase 1 |
| Ginsenoside Re | None of these genes | Early phase 1 |
| Glucagon-Like Peptide 1 | None of these genes | Early phase 1 |
| Hydrocortisone | None of these genes | Early phase 1 |
| Hydrogen Peroxide | None of these genes | Early phase 1 |
| Methylcobalamin | None of these genes | Early phase 1 |
| Montelukast | None of these genes | Early phase 1 |
| Olestra | None of these genes | Early phase 1 |
| Prednisone | None of these genes | Early phase 1 |
| Trehalose | None of these genes | Early phase 1 |
| Cpd 29 | None of these genes | Investigational new drug |
| Amibegron | None of these genes | Preclinical |
| Bay-985 | None of these genes | Preclinical |
| Ds-1558 | None of these genes | Preclinical |
| Aminolevulinic Acid | None of these genes | Unknown |
| Aprepitant | None of these genes | Unknown |
| Arundic Acid | None of these genes | Unknown |
| Beinaglutide | None of these genes | Unknown |
| Bicalutamide | None of these genes | Unknown |
| Bisoprolol | None of these genes | Unknown |
| Bq-123 | None of these genes | Unknown |
| Bq 788 | None of these genes | Unknown |
| Calcium Polycarbophil | None of these genes | Unknown |
| Candesartan | None of these genes | Unknown |
| Carnitine | None of these genes | Unknown |
| Ceramide | None of these genes | Unknown |
| Chenodiol | None of these genes | Unknown |
| Cocarboxylase | None of these genes | Unknown |
| Cyproterone Acetate | None of these genes | Unknown |
| Darbepoetin Alfa | None of these genes | Unknown |
| Dexmedetomidine | None of these genes | Unknown |
| Diquafosol | None of these genes | Unknown |
| Ephedrine | None of these genes | Unknown |
| Epoetin Alfa | None of these genes | Unknown |
| Epoetin Beta | None of these genes | Unknown |
| Eprosartan | None of these genes | Unknown |
| Ertiprotafib | None of these genes | Unknown |
| Escitalopram | None of these genes | Unknown |
| Fimasartan | None of these genes | Unknown |
| Fish Oil Triglycerides | None of these genes | Unknown |
| Fluconazole | None of these genes | Unknown |
| Flurbiprofen | None of these genes | Unknown |
| Formoterol | None of these genes | Unknown |
| Garlic | None of these genes | Unknown |
| Genistein | None of these genes | Unknown |
| Ginger | None of these genes | Unknown |
| Glp-1 | None of these genes | Unknown |
| Gonadorelin | None of these genes | Unknown |
| Hyaluronic Acid | None of these genes | Unknown |
| Ibandronic Acid | None of these genes | Unknown |
| Iloprost | None of these genes | Unknown |
| Insulin, Isophane | None of these genes | Unknown |
| Interferon | None of these genes | Unknown |
| Interferon Alfa | None of these genes | Unknown |
| Interferon Alfa-2b | None of these genes | Unknown |
| Isosorbide Mononitrate | None of these genes | Unknown |
| Ketoprofen | None of these genes | Unknown |
| Lactulose | None of these genes | Unknown |
| Lisinopril Anhydrous | None of these genes | Unknown |
| Lycopene | None of these genes | Unknown |
| Metreleptin | None of these genes | Unknown |
| Mirabegron | None of these genes | Unknown |
| Modafinil | None of these genes | Unknown |
| Nitroprusside | None of these genes | Unknown |
| Norepinephrine | None of these genes | Unknown |
| Olmesartan | None of these genes | Unknown |
| Omega-3 Fatty Acids | None of these genes | Unknown |
| Oxytocin | None of these genes | Unknown |
| Ozone | None of these genes | Unknown |
| Peginterferon Alfa-2a | None of these genes | Unknown |
| Pegvisomant | None of these genes | Unknown |
| Pentaerythritol Tetranitrate | None of these genes | Unknown |
| Perflutren | None of these genes | Unknown |
| Phenylephrine | None of these genes | Unknown |
| Polyethylene Glycol | None of these genes | Unknown |
| Potassium | None of these genes | Unknown |
| Pravastatin | None of these genes | Unknown |
| Protamine Sulfate | None of these genes | Unknown |
| Pyridostigmine | None of these genes | Unknown |
| Regadenoson Anhydrous | None of these genes | Unknown |
| Remimazolam | None of these genes | Unknown |
| Ribavirin | None of these genes | Unknown |
| Rifaximin | None of these genes | Unknown |
| Sevelamer | None of these genes | Unknown |
| Skf-38393 | None of these genes | Unknown |
| Sodium Chloride | None of these genes | Unknown |
| Thyroxine | None of these genes | Unknown |
| Tocilizumab | None of these genes | Unknown |
| Varenicline | None of these genes | Unknown |
| Warfarin | None of these genes | Unknown |
| Zinc Sulfate | None of these genes | Unknown |
The drug data is ChEMBL's, under CC BY-SA 3.0, and came through Open Targets release 26.09.